Complications of Chronic Renal Failure in Children

All the children should have the same right to enjoy their childhood and live a healthy and happy life. However, sometimes, the fate is unfair. Many children have to endure the torments of disease. Especially for those with Chronic Renal Failure, its severe complications do so enormous harm to them.

Renal osteodystrophy

The impaired phosphate excretion results in an elevation of serum phosphate and a drop in calcium thus stimulating the development of renal osteodystrophy. Also the impaired formation of active metabolites of vitamin D results in malabsorption of calcium across the intestinal tract. In addition, the children with Chronic Renal Failure have a skeletal hormone resistance which can contribute to the development of renal osteodystrophy.

Growth failure

The majority of children who have Chronic Renal Failure suffer from significant growth retardation. Among the children with the disease, their tissues have resistance to endogenous and exogenous growth hormone. Moreover, the growth hormone receptor is also inhibited by the disease.

Anemia

When renal function falls below 15% of normal, anemia appears with increasing frequency in Children with Chronic Renal Failure. There are multiple factors attributing to the anemia in children.

* Decreased erythropoiesis

* Shortened red blood cells survival

* Excessive blood losses

* Iron and folic acid deficiency

Frequent infection

For the children with Chronic Renal Failure, they suffer from impaired immunological defense and delayed wound healing, which can give rise to a higher incidence of infection in children.

Other complications

A progressive encephalopathy, seizures,ataxia, chorea, duodenal ulcers and sexual dysfunction have been noticed in the children who have Chronic Renal Failure.


The above has introduced the main complications of Chronic Renal Failure in children. However, if the parents can have their children treated as early as possible, they will be able to avoid developing the above complications. If you feel disappointed about the present treatment of your children, maybe you can change to a new one. If you want to know the latest treatment of Chronic Renal Failure for children worldwide, you can consult our experts on line. Maybe our advices will be helpful your children.