How Is the Prognosis of Purpura Nephritis

Purpura is an allergic disease. It can cause damage to multiple body systems such as joints, intestinal tract etc. Purpura Nephritis is the most serious complication of allergic purpura. Then how is the prognosis of Purpura Nephritis? Will it progress into Chronic Renal Failure?

Some statistics show that about 50% of the patients with allergic purpura have renal injury in varying degrees, in which nearly 15% of the patients develop persistent gross hematuria and/or proteinuria and 18% of them show microscopic hematuria and microalbuminuria. More than 5% of the patients will develop Chronic Renal Failure in several years. The prognosis of Purpura Nephritis varies in different patients and it is mainly affected by the following factors.

1. Age of onset of Purpura Nephritis

The prognosis of Purpura Nephritis in children is favorable. In more than 70% of cases, the disease in children can remit completely. However, the prognosis of the disease among adults is poor.

2. The pathological categories of Purpura Nephritis

Some researches prove that the patients with type IV or severer pathological category are at high risk of developing Chronic Renal Failure. While only 3% of the patients with other pathological categories will develop Chronic Renal Failure.

3. Clinical symptoms of Purpura Nephritis

High blood pressure and proteinuria are two risky factors in worsening prognosis of Purpura Nephritis. If the patients have massive proteinuria or uncontrolled high blood pressure, the prognosis of the disease is usually very bad. Therefore, controlling blood pressure and eliminating proteinuria is very important to improve the prognosis of Purpura Nephritis.

Here the experts remind the patients with purpura that even if they do not present symptoms of renal injury, they should still keep regular checks because the renal injury usually occurs latently within several years after the diagnosis of purpura.


Once the patients are diagnosed with Purpura Nephritis, they should receive proper treatment as early as possible to avoid it from developing into Chronic Renal Failure.