What Are the Complications of Hypertensive Nephropathy

Hypertensive Nephropathy is a leading cause of End Stage Renal Failure. Uncontrolled, the renal injury can cause a series of complications. In return, the complications also can aggravate the disease progression. Therefore, it is very important to prevent the incidence of complication to slow down the progression of Hypertensive Nephropathy. The common complications of Hypertensive Nephropathy are as follows:

1. Glomerulosclerosis and Chronic Renal Failure

If the patients have a poor control of blood pressure over time, it can trigger glomerular ultrafiltration which can lead to glomerulosclerosis. In turn, for renal injury, the kidneys can not secrete hormone renin in charge of regulating blood pressure. As a result, the blood pressure is elevated thus accelerating Hypertensive Nephropathy progression.

2. Cerebrovascular accident

Cerebrovascular accident is a serious complication in Hypertensive Nephropathy with high morbidity. It can lead to disability and even death to the patients. The morbidity of cerebrovascular accident rises with blood pressure. Therefore, the patients should take effective preventive measures to avoid the damage. If they have fatigue, nausea, vomiting, dizziness etc for no clear reasons, they should go to see a doctor immediately.

3. Increased urination at night

In the early stage of Hypertensive Nephropathy, the renal tubule is impaired seriously. As a result, the concentration of urine declines, which can cause frequent urination at night.

4. Swelling

Swelling mainly occurs around eyelids and lower limbs and other loose body part. It is obviously serious in the morning. After activity, it may relieve and even disappear.

5. Protein in urine

The patients with Hypertensive Nephropathy usually have mild proteinuria and microscopic hematuria and urine cast.


The complications of Hypertensive Nephropathy can accelerate the disease progression into Renal Failure. Therefore, the patients should not take proper treatment to stop the disease aggravation as early as possible.