What Is the Prognosis of MPGN

Membranoproliferative glomerulonephritis (MPGN) is a disease that affects glomeruli of the kidneys. For glomerular injury, it can cause massive proteinuria, swelling, high blood pressure etc. The prognosis of MPGN varies from case to case.

When MPGN is associated with another condition or disease such as systemic lupus erythematosis, hepatitis B or C etc, the symptoms can relieve to some extent by successfully treating the associated condition or disease. However, if the associated disease or condition reoccurs, it will trigger MPGN at once. That is because the underlying cause of MPGN is not eliminated.

Alternatively, if MPGN is considered idiopathic, its prognosis is extremely bad. Up to 50~60% of untreated patients will progress to End Stage Renal Failure within 10~15 years.

Therefore, it is very important for the patients with MPGN to receive treatment as early as possible.

MPGN is an autoimmune disease, in which the immune system can not tell the difference between the stuff inside the body like the healthy organs and stuff outside the body such as germs and other things. As a result, the immune system attacks the kidneys thus impairing glomeruli and causing a series of clinical symptoms.

Therefore, regulating autoimmune process is a vital process in inhibiting MPGN progression. If the immune system is corrected, it will recover the normal function in protecting body.

However, the abnormal immune system has impaired the glomeruli of kidneys and affected their functions. To recover the kidney function, the patients with MPGN should take effective treatment to restore the impaired kidney function.

To achieve the above therapeutic effects, our hospital introduces immunotherapy into the treatment of MPGN after many years'research. Immunotherapy is a comprehensive treatment system including traditional Chinese medicine and advanced Immunotherapy and blood purification etc.


Immunotherapy is a breakthrough in treating MPGN. If you are not familiar with the therapy and want to know more about it, it is free for you to consult us on line.