How to Prevent MPGN Type 2 (DDD) Progressing into Renal Failure

MPGN type 2 stands for Membranoproliferative Glomerulonephritis type II. It is also known as dense deposit disease (DDD). It affects more children than adults. Approximately 50% of persons with type 2 MPGN develop Renal Failure 10 years after diagnosis and hyave to require dialysis or kidney transplant to survive.

How does MPGN type 2 occur?

Most instances of MPGN type 2 are caused by other diseases or disorders, including autoimmune disease such as systemic lupus erythematosis (SLE), chronic infections like hepatitis B etc.

MPGN type 2 is an autoimmune disease, in which the immune system attacks filters (glomeruli) in kidneys mistakenly. When the outside harmful substances such s lupus virus, hepatitis B virus invade into body as antigens, the antibodies in body fail to defeat them immediately for autoimmune disorder. As a result, the antigens and antibodies bind to each other and form immune complexes in blood and flow into kidneys through circulation.

Afterwards, the immune complexes attract inflammatory factors ceaselessly thus impairing the filters in kidneys and causing mesangial cell proliferation. If the immune complexes can not be removed and the inflammation keeps going on, the kidneys will fail at a very fast speed.

How to prevent MPGN type 2 developing Renal Failure?

As mentioned above, the patients may develop Renal Failure within several years after the diagnosis. It is urgent for the patients to receive proper treatment as early as possible.

In China, the combination of Micro-Chinese Medicine Osmotherapy and Immunotherapy is applied to treat MPGN type 2 and has showed an enormous effect.

The therapeutic mechanism of the therapy is as flows:

Micro-Chinese Medicine Osmotherapy:

1. Dilate blood vessels: It can improve the microcirculation in kidneys to relieve the renal ischemia and anoxia.

2. Anti-inflamation: It can reduce the inflammatory factors to infiltrate into kidneys. Hence, it can prevent further damage to mesangial cells.

3. Degradation: It can degrade the immune complexes in membrane and mesangial area. Finally, the degraded immune complexes will be passed out of body in urine.

As a result, Micro-Chinese Medicine Osmotherapy can make a favorable environmental for repairing the impaired kidney cells.

Immunotherapy

Immunotherapy refers to infusion of healthy cells into the body of the patients with MPGN type 2. Immunotherapys are a class of primitive cells with potentials of differentiation. In right body condition, they can differentiate into new cells with specialized function to replace the diseased cells to function.

After Immunotherapy are infused into body, they can differentiate into new kidney cells with the help of inducing agents to replace the impaired and necrotic cells to function. As a result, the kidneys will be restored very well.


Moreover, Immunotherapy can stimulate the body to produce normal immune cells to rebuild the new immune system. Hence, it will be able to eliminate the relapse problem of MPGN type 2.