How to Prevent Hyperuricemic Nephropathy

Hyperuricemic Nephropathy is renal damage caused by hyperuricemia. For abnormal metabolism of purine, more uric acid is produced, but can not be discharged out of body normally thus causing uric acid level in blood to increase. Therefore, controlling hyperuricemia is the key to prevent and treat Hyperruricemic Nephropathy.

1. Control diet

The patients with Hyperuricemic Nephropathy should avoid eating food with high purine such as animal offal, fish, and sea food and so on. In addition, they should limit the intake of meat for it contain too much purine and also can make urine become acidic. In addition, they should control the protein intake and keep its intake within 1 gram/ kg per body weight.

2. Drink more water

Keep the urine output volume between 2000~3000 ml is beneficial for the discharge of uric acid. If the patients drink more water before sleeping, it can promote the discharge of the small kidney stone and prevent infection.

3. Alkalify urine

Alkalifying urine can prevent the formation of uric acid stone and also can promote the dissolving of uric acid stone. It is proper to keep PH within 6.5~6.8.

4. Treat hyperuricemia in time

The patients should take some medicines that are effective in lowing uric acid under the doctors’ guidance. The medicines include two types: one can promote the discharge of uric acid and the other can restrain the formation of uric acid. The medicines which can increase the discharge of uric urine can decline the reabsorption of uric acid by renal tubular. However, if the patients have renal insufficiency, the medicines can improve the discharge of uric acid thus causing uric acid crystal, which can aggravate the disease. Therefore, this part of patients is not suitable to take the medicines.


If the patients can keep a proper heath care and prevent and treat hyperuricemia in time, they will be able to avoid or treat Hyperuricemic Nephropathy effectively.