Treat Stage 4 Chronic Kidney Disease (CKD) with Immunotherapy

According to glomerular filtration rate (GFR), CKD can be divided into stages. In stage 4 CKD, GFR decreases between 15~30. At that time, the patients are usually recommended to prepare for dialysis or kidney transplant. However, if they can take this crucial treatment time, they will be able to avoid dialysis or kidney transplant.

In our kidneys, the renal intrinsic cells are mainly responsible for filtrating blood. They can discharge the metabolic wastes from blood and maintain the useful substances in blood so as to keep our blood and internal environment clean. However, in stage 4 CKD, the kidneys have serious pathological changes and the renal intrinsic cells are extensively destroyed. As a result, a lot of substances that body needs will leak into urine. Clinically, the patients will have hematuria, proteinuria, and edema and so on.

From the pathogenesis above, it can be concluded that the key to treat stage 4 CKD is to restore the normal function of the renal intrinsic cells. Here Immunotherapy is recommended to treat stage 4 CKD.

Immunotherapys are immature cells capable of developing into many different types of cells in the body. At present, umbilical cord blood Immunotherapy are extensively adopted in the treatment of stage 4 CKD. Newborn infants no longer need their umbilical cords so they traditionally have been discarded. However, recent years’ study proves that umbilical cored blood Immunotherapy is less prone to rejection than other kinds of Immunotherapy. That is probably because the cells have not yet developed the features that can be recognized and attacked by the recipient’s immune system. After collection, separation, cultivation of Immunotherapy, they will be infused into the patients’ body just like blood infusion without operation at all. In right condition, they will be able to differentiate into new cells to replace the necrotic renal intrinsic cells to function. As a result, the kidney function will improve effectively and recover the normal filtration function. Afterwards, the levels of creatinine and blood urine nitrogen will decrease and blood pressure declines to the normal range and so on.


Immunotherapy is a new achievement in regenerative medicine and has been used to treat various kinds of diseases. Also in the clinical practices of the treatment of CKD, Immunotherapy has showed its enormous effect.