High Blood Pressure Can Cause Renal Injury

Hypertensive Nephropathy is the secondary complication of chronic high blood pressure. If the patients keep poor control of their blood pressure over time, it is very likely to cause renal injury.

Generally speaking, in the early period of high blood pressure, it can not lead to obvious kidney lesion. However, the patients’ adaptive capacity to high sodium and increased blood volume declines. For example, if the patients with high blood pressure eat much salty food or drink a large amount of fluid, they are very likely to have edema or blood pressure to rise. The patients with high blood pressure should pay more attention to the mentioned abnormal symptoms for those may be the early sign of renal injury.

After that, the concentrating ability will decline gradually. It presents increased urination at night, higher pressure in glomeruli thus leading to increased excretion of microdose albumin in urine.

Generally speaking, kidneys begin to have mild or even medium renal arteries sclerosis and then renal parenchymal ischemia, withering, fibrosis. Consequently, the renal function will decline gradually and the levels of creatinine, urea nitrogen and uric acid rise.

When the kidneys can not get enough blood supplements, the endothelium of renal blood vessels will be damaged. As a result, the substances secreted by kidneys in dilating and expanding blood vessels lose balance thus making the primary blood pressure higher. Consequently, high blood pressure and kidney disease promote each other and lead to Renal Failure gradually.

If the patients with high blood pressure have the following symptoms, they should to go further exam to find out if they have renal injury.

1. Increased urination at night;

2. The patients are tested out to have protein in urine in urine test;

3. In blood test, their creatinine level is slightly higher than the normal level( 1~2 mg/dl);


However, in most cases, the above symptoms are often neglected by the patients so they often miss the best therapeutic opportunity. For the patients with high blood pressure, they should go to do renal check, urine test and blood test regularly, especially those with a long history of high blood pressure. In this way, they will be able to decline the renal injury caused by high blood pressure greatly.