Why Do Patients with Kidney Disease Have Vomit and Nausea

Vomit and nausea are common symptoms for the patients with Kidney Disease, which is very likely to cause them malnutrition and immunity to decline. Therefore, it is very necessary for the patients to know the causes of vomit and nausea so as to prevent their occurrence.

1. Nephrotic Syndrome

For the patients with Nephrotic Syndrome, they lose a large amount of protein in urine thus leading to hypoproteinemia. The patients not only have edema in their limbs, but also have edema in gastrointestinal tract, which can lead to digestive system dysfunction. Clinically, the patients often have vomit, nausea and diarrhea.

2. Hyponatremia

For the patients with Kidney Disease, the patients usually have hyponatremia(serumsodium< 130 umol/L) due to various causes.

(1) Excessive water build-up in body and infusion of fluid cause dilutional hyponatremia;

(2) Limit salt intake

(3) When the patients suffer from metabolic acidosis, the sodium outside cells transfers into cells;

(4) Some patients with Interstitial Nephropathy, their renal tubules lose the reabsorption ability;

(5) If the patients use diuretic irrationally in the long term, it is very likely to lead to hyponatremia.

3. Metabolic acidosis

For metabolic acidosis, some patients with Chronic Renal Failure can not discharge acid metabolic product thus accumulating in body and leading to acidosis. Consequently, the patients will have vomit and nausea.

1. For some patients, after they use cyclophosphamide for a period, they may have vomit and nausea. That is because the medicines damage their liver function thus causing vomit and nausea. Once they stop using cyclophosphamide , their liver function will recover gradually and the vomit and nausea will also disappear.

For the patients with Chronic Renal Failure, the uria decomposes into amine with the help of urease thus irritating intestinal mucosa and leading to inflammation and ulcer. Uremic toxins, especially medium molecular substances and so on can influence the metabolism of cells thus causing cell edema. As a result, the patients will have vomit and nausea.


The above has introduced the common causes of vomit and nausea. The patients should find out the specific causes of their vomit and nausea and adopt relative treatments. In this way, they will be able to get a better therapeutic effect.