Common Sense about Glomerulonephritis (Nephritis)

Glomerulonephritis is also named as Nephritis. It is allergic reaction featured with glomerular damage and is a common cause for Renal Failure.

Clinically, Nephritis mainly presents proteinuria, hematuria, edema, high blood pressure and so on. As this kind of disease has latent characteristics, Nephritis can develop for a long period asymptomatically. Therefore, it is often be neglected by the patients thus missing the best therapeutic opportunity. Once the renal fibrosis process starts, the renal function will reduce gradually and finally develop into Renal Failure and Uremia. The patients have to depend on dialysis or kidney transplant to preserve their lives.

According to the causes of Nephritis, it can be divided into two types: Primary Nephritis and Secondary Nephritis.

Primary Nephritis is an independent disease and the pathological changes involve kidneys featured by glomerular injury. It is the most common leading cause of Renal Failure. It usually occurs after infections like streptococcal infection.
Secondary Nephritis is a part of the systemic diseases like immune diseases lupus erythematosus (SLE), allergic purpura, metabolic diseases Diabetes, amyloidosis or vascular diseases. With the development of the primary disease, they will gradually damage glomerular capillaries leading to kidney injury.

As Nephritis is a common leading cause of Renal Failure, it is very urgent for the patients to receive treatment as early as possible.

As the glomeruli are damaged seriously, it is the key to restore the impaired glomeruli in the treatment of the disease. Glomeruli are the filters composed of the renal functional cells including epithelial cells, endothelial cells and mesangial cells. Therefore, repairing the damaged renal functional cells is the key in restoring glomeruli. In Nephritis, the impaired renal functional cells can be divided into three types: cells with complete function, cells that can be reversed by medicines and totally necrotic cells.

As for the second types, Chinese medicine can dilate blood vessels thus improving the blood supply to kidneys. Moreover, the medicines can provide the some nutrients for the self-repairing of the damaged cells. Therefore, the impaired cells will be able to regain their normal function.

However, for the totally necrotic cells, we should use new cells to replace them. Immunotherapy makes this therapeutic goal realize. Immunotherapys can differentiate into new cells to replace the necrotic ones to function.


In this way, the glomeruli will be able to restore their normal function so as to recover the normal renal function.