Clinical Symptoms of Gouty Nephropathy

Gouty Nephropathy is the secondary Kidney Disease of gouty. It usually occurs latently so some clinical symptoms of Gouty Nephropathy are often neglected by the patients. Here the article will list the clinical symptoms of Gouty Nephropathy. If the patients with gouty have one or several of them, they should do further exam to find if they have renal injury.

In the early period of Gouty Nephropathy, the patients usually have mild back pain and persistent or intermittent proteinuria. In some cases, the patients may be companied with mild edema. About 60% of cases, their blood pressure will rise moderately. As the renal tubule is damaged, the urine concentration and dilution functions are damaged. Moreover, the patients’ urine is acid and its PH is below 6.0.

Gouty Nephropathy develops progressively. In its late period, the glomeruli are injured. As a result, the creatinine clearance rate declines and blood creatinine level and urea nitrogen level rise.

About 90% of the patients with Gouty Nephropathy are complicated with urate stones due to hyperuricemia, acid uria and dehydration. In some cases, the urate stone can obstruct renal tubule and urinary tract thus leading to renal colic and gross hematuria. Moreover, once urate stone obstructs urinary tract, it is very likely to lead to urinary tract infection.

About 80% of the patients with Gouty Nephropathy have acute and chronic arthritis. Acute arthritis often occurs suddenly and alcohol, overwork, gluttony, colds are its inducements. It usually occurs at night and the patients have intense pain suddenly. If the patients do not treat acute arthritis when it occurs every time, it will develop into chronic arthritis gradually. The patients may have joint pain, deformation, rigidity and so on.


The above article has introduced the clinical symptoms of Gouty Nephropathy. If you have one or several symptoms above, you should go for further exam and find if you have renal damage as early as possible.