Generally speaking, the prognosis of Membranous Nephropathy is not good and
many patients develop End Stage Renal Failure. Therefore, you should know
firstly know if you a Membranous Nephropathy and then receive relative treatment
in time so as to stop the further progression of the disease. It is very
necessary for you to have a comprehensive understanding of Membranous
Nephropathy.
Membranous Nephropathy can be found at any age, but about 80~90% of the
patients are above 30 years old. Its incidence is especially high among the male
above 50~60 years old. The onset of the disease is very latent and the patients
usually do not have prehistory of the upper respiratory tract infection. About
70~80% of the patients with Membranous Nephropathy have Nephrotic Syndrome and
30~50% of children is complicated with microscopic hematuria and rarely in the
adults. About 13~55% of the patients have high blood pressure when they have
first diagnosis.
Clinically, in most cases of Membranous Nephropathy, the patients have a
large amount of proteinuria. Most of the children’ proteinuria can recover by
itself within five years. Among the adult patients, about 25% of them can remit
from proteinuria by themselves.
Generally speaking, Membranous Nephropathy progresses very slowly, but about
10% of the patients have had renal insufficiency when they go for treatment for
the first time. Proteinuria is the main cause in aggravating renal injury.
Moreover, high blood pressure, edema and so on also are dangerous factors in
aggravating Renal Failure.
For some patients with Membranous Nephropathy, their renal function may
decline at a fast speed. Once the renal function aggravates sharply, it often
imply the patients may be also complicated with other Kidney Diseases. Another
reason for drastic decline in renal function is acute bilateral venous
thrombosis. In this case, the patients may have a large amount of proteinuria,
declined effective blood volume. Clinically, the patients often have gross
hematuria, back pain and other symptoms besides the aggravation of renal
function. Moreover, medicine is also a common inducement of renal function
aggravation like diuretic, antibiotics and so on.
The above has introduced some common knowledge of Membranous Nephropathy. If
you have one or several symptoms mentioned above, you had better go for further
inspection to find if you have renal injury in the first time.
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