What Are the Clinical Symptoms of Diabetic Nephropathy

If patients with Diabetes can not control their disease very well for a long time, it is very likely to cause to them. It threatens patients’ lives seriously and is an important inducement of death for them. Therefore, it is very important for patients to treat the disease as early as possible. The following article will list the main symptoms of Diabetic Nephropathy. When patients have the following symptoms, they should go to see a doctor at once.

1. Proteinuria

The patients with Diabetic Nephropathy do not have clinical proteinuria in the early time. Only by radioimmunoassay, the patients can be inspected to have microalbuminuria. Proteinuria is the sign of clinical Diabetic Nephropathy. After the disease develops into clinical Diabetic Nephropathy, the protein in urine will increase gradually. Usually, the patients will have mass proteinuria( >3.5 grams per day) in about 3~5 years thus causing Nephritic Syndrome.

2. Edema

Clinically, in the early time, the patients do not have edema. A minority of patients may have mild edema before their protein in plasma declines. Once the patients begin to have mass protein and very low protein in plasma, they will have serious edema. What’s worse, some patients even have ascites and hydrothorax.

3. Hypertension

Hypertension is an early clinical symptom of Diabetic Nephropathy. In the early time, the patients mainly have intermittent high blood pressure, and gradually, it will develop into persistent high blood pressure. Hypertension can increase the excretion of urine protein thus causing more damage to their renal function.

4. Anemia

As patients’ renal function declines, it can not be able to secrete enough hemopoietin. Moreover, some patients have poor appetite, vomit and nausea, it can cause body to have raw material such as iron abs folic acid for producing blood.

5. Declined renal function

Before patients develop into clinical Diabetic Nephropathy, the patients’ renal function declines very slowly. However, after the patients begin to have persistent proteinuria, especially mass proteinuria , their renal function will declines sharply. Every month, their creatinine clearance rate can decline as high as l ml/ minute. As a result, the patients will have insufficiency renal function gradually, At the same time, their cretinine level and urea nitrogen level will increase. The patients can develop into End Stage Renal Failure in several years.

In order to prevent Diabetes from causing Diabetic Nephropathy, it is very important for patients to have treatment as early as possible.

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