Not All Patients with Renal Failure are Suitable for Kidney Transplant

Kidney Transplant is an important substitutive therapy for the patients with End Stage Renal Failure. Generally speaking, there are no absolute contradictions, but relative contradictions for Kidney Transplant. If the patients meet the following requirements, they will be able undergo Kidney Transplant.

(1) The patients with End Stage Renal Failure are between 12~65 years old. However, if the patients are older than 65, but they keep normal heart, lung and liver functions and also do not have serious blood vessels diseases and can tolerate the operation, they can undergo Kidney Transplant.

(2) After a period of hemodialysis or peritoneal dialysis, their kidney disease condition keeps well and there is no potential infection nidus. Moreover, the patients can endure the operation.

Besides the above requirements, Kidney Transplant still has contradictions.

1. Absolute contradictions

(1) Uremia is not caused by kidney disease, but is only a local manifestation of systemic diseases like periarteritis nodosa. For those patients, they are not suitable for Kidney Transplant as the transplanted kidney will have the same pathological change after Kidney Transplant.

(2) If the patients have systemic serious infection or active tuberculosis, they should not undergo Kidney Transplant. That is because immunosuppressive agents can aggravate infection and make tuberculosis spread thus leading to serious result.

(3) If the patients have the following diseases, malignancy tumor, heart failure, chronic breath failure, coagulation disorder, Aids, mental disorder, cirrhosis, they should not undergo Kidney Transplant.

2. Relative contradictions

(1) Ulcer: If the patients with End Stage Renal Failure has active ulcer, they should not undergo Kidney Transplant until ulcer is cured. That is because the application of large dosage of hormone can cause digestive tract ulcer bleeding and perforation and other complications.

(2) Hepatitis B and C: If the patients with End Stage Renal Failure carry Hepatitis B Virus (HBsAg positive) and Hepatitis C Virus (anti-HCV positive), they are not the absolute contradictions for Kidney Transplant. However, the patients with the above Hepatitis should check HBV-DNA and HCV-RNA. If the check results are negative and also liver function is normal, the patients can undergo Kidney Transplant. If the results are positive, this proves that Hepatitis virus duplicate in body. In this case, the patients should consider undergoing Kidney Transplant until the check results of HBV-DNA and HCV-RNA become negative. If the Hepatitis B and C Viruses are positive and also the patients have cirrhosis or pathological change before cirrhosis, the patients should not receive Kidney Transplant.

(3) Infection nidus: Before Kidney Transplant, the patients should do careful checks to find if they have infection nidus such as pneumonia and trachitis. If the patients have infections, they should postpone their Kidney Transplant and undergo it after curing the infection. That is because after Kidney Transplant, the patients need to use a large amount of immunosuppressive agents, which may cause immunity to decline. If the patients have potential infection nidus, it is very likely to occur and influence the effect of Kidney Transplant.


In order to improve the effect and safety of Kidney Transplant, the patients with End Stage Renal Failure must know more about the common knowledge about Kidney Transplant. Meanwhile, the patients should consider the risk and complications of Kidney Transplant. If possible, they should try a better therapy. If you want to what you should do before Kidney Transplant, please consult us on line or email to kidney-treatment@hotmail.com.