Pathological Categories in Causing Primary Nephritic Syndrome

Primary Nephritic Syndrome is caused by Primary Glomerular Diseases. The pathological categories of Primary Nephritis Syndrome mainly include the following types:

1. Minimal change nephritis

It is common among children, especially those between 2~ 6 years old. Clinically, its onset is quick after colds. The patients usually can develop Nephritic Syndrome in a short time. The incidence of microscopic hematuria is only 15~20 without gross hematuria. Generally, the patients also do not have hypertension or decline in renal function. The recurrence rate of the disease can reach 60%. Without effective treatment, the disease can develop into FSGS.

2. Mesangial Proliferative Glomerulonephritis

It mainly occurs among teenagers. If the patients have prehistory of infection, the disease can occur quickly and may cause Acute Nephritic Syndrome. In other cases, the disease can occur latently. The incidence of Nephritic Syndrome among IgA Nephropathy is about 15% and 30% in the non-IgA Nephropathy patients. Nearly all patients with IgA Nephropathy have hematuria and its incidence is about 79% in the non-IgA Nephropathy patients. The incidence of Renal Insufficiency and Hypertension goes up with the disease development.

3. Mesangial Proliferative Glomerulonephritis

It is common among adults. Its onset is quick among patients with prehistory infection, or it often occurs latently. About 60% of the patients have Nephritic Syndrome together with hematuria. The disease usually progressively develops and renal insufficiency, high blood pressure and anemia can appear in early time.

4. Membranous Nephropathy

It mainly occurs in the elder. It usually occurs latently. The incidence of Nephritic Syndrome is about 80%. In some cases, the patients have microscopic hematuria, but do not have gross hematuria. About 1/3 of cases, the disease progresses slowly and it can develop into renal insufficiency in 5~10 years.

5. FSGS

It is common in teenagers. The onset of the disease is latent. Onset, the patients may suffer from FSGS primarily or it is developed by minimal change nephropathy. Among patients with FSGS, the incidence of Nephritic Syndrome is 50%~70%. The incidence of hematuria is about 70% and gross hematuria is also can be seen. Renal insufficiency and hypertension are also very common.


As there are various pathological categories of Nephritic Syndrome, it is very important for patients to know the pathological category of their disease firstly so as to receive relative treatment in time. If you are still tormented by kidney disease, you can ask for help on our experts on line or email to kidney-treatment@hotmail.com.