Mysterious Relations between PKD and Hypertension

The majority of patients with Polycystic Kidney Disease (hereinafter called PKD) is adjoint with Hypertension. After massive clinical researches, there is an cause and effect between PKD and Hypertension.

The pathological agent of PKD Hypertension is affected by cysts size and numbers. With cysts progression, they can compress renal blood vessels, causing local blood flow to decrease. After getting this signal, renal receptor can report this to juxtaglomerular cell which can secrete more rennin. The content of angiotensin can increase, which makes blood vessel shrink and incur Hypertension.

Generally, PKD patients’ renal function is to be damaged or have been damaged when they present blood pressure increase. And Hypertension is regarded the landmark when PKD progresses from the stage of symptoms to the stage of Renal Insufficiency. it is necessary for PKD patients to pay attention to reduce blood pressure.


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