The Underlying Relations Between PKD And Hypertension

The majority of people know that high blood pressure can cause Coronary Disease and Stroke. But few people realize that there is a relation between high blood pressure and Polycystic Kidney Disease (hereinafter called PKD). Medical research shows that high blood pressure can damage kidney. Similarly, renal injury can also incur high blood pressure. In other words, there exists an underlying link between PKD And Hypertension, and one's lesion will definitely affect the other.

Many PKD patients take hypotensor to control their blood pressure, but these hypertensors can further damage unsound renal function which probably develops into Hypertensive Nephropathy and Renal Failure ultimately. As we know,kidney is a viscera which composes of various micro blood vessels. And these micro blood vessels may present arteriosclerosis if high blood pressure cannot be curbed properly. That is why most Hypertension patients have renal function damage to some extent. These damages may be aggravated with age if they could not be controlled and treated immediately. With its further progression, glomerular sclerosis, renal mesenchyma fibrosis can occur. At last, patients have to suffer from Renal Insufficiency and even Uremia.

Reversely, PKD can also induce Hypertension. The more severe PKD patients’ renal function decreases, the higher their blood pressure increases. In the end stage of Renal Failure, over 80% PKD patients have apparent Hypertension. Just because of this, the progress of renal injury will be accelerated if the sufferer has Hypertension.

PKD patients with Hypertension must take kidney examination regularly. In the clinical practices, there are two kinds of tests generally. One is based on renal morphology and the other is related with renal function. The former one can be detected by Type-B Ultrosound Examination, CT and etc. the latter one refers to Blood and Urine Routine Test. It is advisable for PKD patients with Hypertension to take routine tests so that they can grasp their disease properly. If there is abnormal urine protein and erythrocyte in their urine or blood routine test presents Glomerulus Filtration Rate (GFR) declines and Serum Creatinine (Scr) increases etc. , this manifests that their renal lesion needs to get treated immediately.

Besides, PKD patients should also closely observe the variation of their body. PKD patients with Hypertension have no apparent symptoms in early or middle stages, but they need to notice that Edema in eyelid and lower limbs is an implication of renal damage. And if patients present bad appetite, nausea and vomiting, anemia, easy fatigue and even lumbago, bad spirit, their disease may develop into middle and final stage.

Actually, any complication has a direct or indirect relation with another, so we need to make comprehensive consideration when we take treatment and medicines. In other words, we cannot treat one disease but ignore other diseases. We must realize their cause and effect then we can treat them radically.


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