Glomerulonephritis refers to the inflammation of glomeruli featured with
proteinuria, hematuria etc. Some researches prove that tripterygium wilfordii
has some effect in slowing the progression of glomeruli.
Tripterygium wilfordii is a kind of traditional Chinese medicine and has been
used for centuries as an-inflammatory agent. It contains the active constituents
which are diterpenoids like triptolide and tripdiolide, alkaloids etc. The
diterpene triptolide is considered the major active component in tripterygium
wilfordii.
Tripterygium wilfordii has an anti-inflammation function and plays the role
of immunosuppressive drugs.
In Glomerulonephritis, the immune complexes in glomeruli can cause trigger an
inflammation thus damaging the epithelial cells, mesangial cells etc.
Tripterygium wilfordii can inhibit the abnormal inflammation and relive the
damage to renal tissues and cells. Also, tripterygium wilfordii also can block
the abnormal immune response and reduce the immune complexes formation to some
extent.
In addition, tripterygium wilfordii can provide some effective ingredients
which can promote the self-repairing of the epithelial cells. Therefore, it can
reduce the leakage of protein to some extent.
As tripterygium wilfordii is a kind of natural herb medicine, it does not
cause any adverse side effects to the patients with Glomerulonephritis.
Although tripterygium wilfordii has so many effects in the treatment of
Glomerulonephritis, the patients can not get a good recovery just relying on
this single herb medicine. In fact, in traditional Chinese medicine, every
prescription is composed of four to sixty types of herb medicines. Those herb
medicines are interacted and influenced to act and treat the disease from many
aspects.
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