Latent Nephritis: Pathology ,Symptoms, Treatment

Latent Nephritis is also called asymptomatic hematuria and/ or proteinuria. Generally, it is not complicated with swelling, high blood pressure or renal function damage. In most cases, Laten Nephrits is inspected out in physical examination. Most of the patients do not have obvious symptoms or signs. Only a part of the patients have back pain, fatigue, gross hematuria or other typical symptoms.

Pathology of Latent Nephritis

The pathlogical changes in Latent Nephritis are usually mild like mininal change, mild mesangial proliferative glomerular nephritis and focal segmental glomerular nephritisn etc. According to the pathlogical changs, mesangial proliferative glomerular nephritis can be divided into IgA Nephropathy and non-IgA Nephropathy.

Clinical symptoms of Latent Nephritis

Asymptomatic hematuria

Persistent microscopic hematuria and/or frequently occuring gross hematuria are the main clinical sympoms of Latent Nephritis. It mainly occurs among the adults without asymptomatic symptoms and signs. In most of cases of Latent Nephritis, microscopic hematuria is inspected out in physical examination.

The microscopic hematuria featured with persistence and frequent occurrences. A part of the patients may have transient gross hematuria, but it often disappears in a very short time.

Asymptomatic proteinuria

The proteinuria is usually persistent. The amount of urine protein is less than 2g/d mainly albumin. The patients with Latent Nephritis usually are not accompanied by swelling, high blood pressure and the renal function is generally normal. The blood test usually does not show abnormalities. Asymptomatic proteinuria can last for several years. For the patients with hematuria and proteinuria, their prognosis is usually poor that those with hematuria along.

Conventional therapy

1. The patients with Latent Nephritis should take regular tests including urine test, renal function test and high blood pressure test.

2. Protect renal function and avoid the factors that may cause damage to kidneys

3. If the frequnetly occuring tonsillitis is closely associated with hematuria and proteinuria, the patients should take extirpate tonsillitis.


4. For the patients with much proteinuria, they should use ACEI group.