Why do patients with Polycystic Kidney Disease (PKD) have the symptom of
anemia? When Polycystic Kidney Disease (PKD) develops into renal insufficiency
or renal failure, patients may have the symptom of anemia. In the blood test,
the report may show the low level of hemoglobin. And in clinical, patients may
feel tired and lacking of strength, and the patients with the symptom of anemia
may look pale. Then why do patients with Polycystic Kidney Disease (PKD) have
the symptom of anemia?
The main cause of the symptom of anemia is the damage to the kidney. With the
enlargement of the cysts, they will compress the normal renal tissues, leading
to the ischemia and anemia of the glomerulus. Glomerulus is the basic unit of
the kidney’s filtration function. And there are five kinds of renal intrinsic
cells, playing different roles on the kidney’s filtration procedure. And the
ischemia and anemia will lead to the damage of the renal intrinsic cells,
causing the necrosis of the glomerulus. And the renal function will decline
gradually.
With the damage of the glomerulus and the decline of the renal function, the
secretion function will decline. At this time, kidneys are failed to secret
enough hemopoietin to meet the demand of the body, which is one of the main
causes of the symptom of anemia. Besides, as for Polycystic Kidney Disease
patients who have developed to the stage of renal insufficiency or renal failure
stage, there is large quantity of toxins, which will decrease the survival time
of the red blood cells.
And the decrease of intake of iron and increase of the iron loss will lead to
the insufficiency of the combining of the red blood cells. All of these factors
can lead to the Polycystic Kidney Disease patients suffering from the symptom of
anemia.
To treat the symptom of anemia caused by the Polycystic Kidney Disease,
patients need to process from its root cause-renal damage.
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