The Symptoms of Alport Syndrome

Alport syndrome is a inheritary kidney disorder. Thus, patients need to pay attention to both the symptoms of alport syndrome involving in kidney damage, and the damage to other organs. The prognosis of alport syndrome is different from person to person.

● The symptoms of Alprot Syndrome

The symptoms of kidney damage: Blood urine is the commonest symptoms in Alport Syndrome. 68% Alport syndrome have blood in the urine. About 67% men with Alport syndrome develop gross hematuria before 10-15 age. Gross hematuria can occur following upper respiratory tract infection or overwork.

Protein in the urine is another symptom in patients with Alport syndrome. With age or the presence of blood in the urine, patients can develop persistent proteinuria. The incidence of nephrotic syndrome is 30-40 percent. Under this case, it often has a poor prognosis. Often, 40 aged women develop end-stage renal failure. Sometimes, young people will develop end-stage renal disease.

● Other Symptoms:

Sensorineural hearing loss: It happens to people with ALport Syndrome and audiomery is necessary. The incidence of sensorineurial hearing loss is 81% and 19%.

Eye disease: The youngest patients 13 age with Alport Syndrome develop eye disease. Generally, the eye disease caused by Alport syndrome does not affect the sight. 60% male patients and 70% female patients will develop this disease.

The Latest Treatment for Chronic Kidney Disease

Immune block therapy is an important part of chronic kidney disease treatment.
Based on immunology, immunotherapy for chronic kidney disease is put forward, as one part of which immune block plays an important role on the treatment.

95% chronic kidney disease is caused by the immune disorder. Normal immune system is to fight with the germs and bacteria to keep people healthy. When immune system begins goes wrong, the foreign body would destroy the healthy tissues or organs. If the kidneys are destroyed, kidney damage will occur, causing chronic kidney disease.

Thus, immune block is to stop the foreign body destroying the kidneys to achieve the goal of protecting kidneys.

● What is immune block therapy?

Immune block therapy is to restrain the extreme inflammatory reaction by immune depressant with low effects. it aims to stop the inflammatory reaction in the kidneys to prevent the foreign body damaging the kidneys.

● What are the methods in immune block therapy?

In fact, we use various immunosuppressive agents. At present, glucocorticoid is the commonest medicine used to treat kidney disease. The immune block therapy is a therapy which uses more types of immunosuppressive agents with lower side effects that include:

1. Drugs which treats the autoimmune diseases such as rheumatoid arthritis and leukemia. It shows it plays great role on the chronic kidney disease treatment.

2. Monoclonal antibody medicines, the usage of which is a breakthrough in the treatment of chronic kidney disease. Choose the monoclonal antibody medicine which can block the kidney fibrosis.

3. Use glucocorticoid to improve the immunity.

In summary, the immune block therapy is to block the inflammatory reaction.

● What should you expect from the immune block therapy?

With experience and techniques, we are more confident to treat the chronic kidney disease.

Remove the inflammation fast.

Accurate diagnosis makes sure the effects of medicines.

It is an update treatment for chronic kidney disease.


Immune block therapy is a new therapy for chronic kidney disease. Not only does it releases the symptoms but also regulate and rebuild the immune system.

Exercise Plays a Role on Diabetes Management

Diabetes is a chronic kidney disease which can be controlled by proper medicines, exercise, medications and insulin injection. There are two major types – type 1 diabetes and type 2 diabetes. No matter what type you have, it is necessary to take steps to control blood sugar. Exercise plays a role on diabetes management.
It is proved that exercise helps control the diabetes, improve life quality with more joy. But diabetics need to pay more attention to the amount and mode of exercise and announcement, in order to avoid the adverse events.

● Exercise benefits the diabetics which can:

Reduce blood sugar

Enhance the effect of insulin

Burn fat and lose weight

Anneal the heart, lung and bone

Make people feel release and improve the immunity.

Although exercise brings a lot of benefits a lot, considerations is informed to the diabetics. Choose exercise according to the heart rate. The appropriate heart rate = 170-age. It is better to do exercise for 40-50 minutes 3-4 times every week.

● Exercise suiting the diabetics includes:

Exercise with minimum strength (30 minutes): walk, housework, TaiChi, and shopping.

Exercise with low strength (20 minutes): social dance, going downstairs, biking
Exercise with moderate strength (10 minutes ) slow running, going upstairs,
Exercise with high strength: skipping swimming, playing basketball.

● Not every diabetic is suitable to do exercise.

1. Diabetics who having a poor control of diabetes.

2. Diabetics, complicated by high blood pressure.

3. Diabetics with blood sugar beyond 11.1 mmol/l or more 10% glycoylated hemoglobin.

4. Diabetics who develop persistent proteinuria and kidney dysfunction.

5. Diabetics complicated by acute infection, pulmonary phthisis, and liver disease.

Proper exercise benefits the diabetics but violent exercise has negative effects on diabetics.


Diabetics consult your doctor what type of exercise is suitable to you in order to avoid the adverse events.

Another New Form of Chinese Herbs for Kidney Failure

Chinese herbs have been used to treat kidney failure for thousands of years. Its therapeutic effects have been recognized in the world. Here, a new form of Chinese herbs for kidney failure is introduced – Medicated Bath.

◆ Overview of Medicated Bath

Medicated Bath is a therapeutic bath for kidney failure. Before starting the process of medicated bath, the temperature is measured to make sure it within 35 and 37℃. Subsequently, according to individual condition, the prescribed Chinese herbs fluid is dispersed in water, and then soaks the body in the medicated fluid for half hours, which can make you sweat much. The reason for the treatment is explained to the patient, and instructions are given not to get out of the tub without assistance and not to add water without calling the nurse. The medicated bath is usually soothing, relaxing and comforting for the patient. During the procedure, there are nurses will instructing the patient fully and ensuring comfort.

◆ How does Medicated Bath work on Kidney failure?

Medicated bath treats kidney failure through skin.

Skin is a miracle organ which is the largest organ in terms of the size and takes up 5-15 percent of the total weigh. Kidney failure closely links to the skin.

Skin can breathe by sweat pore, directly absorbing oxygen from the air and meanwhile filtering the carbon dioxide. Skin is able to keep the balance of acid and alkaline and increase oxygen in the blood.

Skin can discharge excessive fluid. In normal people, 600-700 ml fluid is discharged silently. It also can discharge some wastes such as urea, lactic acid and fatty acid. Thus, it is a good way to treat kidney disease through skin.
Medicated bath is to discharge toxic substances and excessive fluid in the sweats, replacing the kidney function. The size of skin is large. If some medicines can promote sweats, effective ingredients can combine with the toxic substances by skin and then removing them out of body. This way can replace part of kidney function. The Chinese herbs are to work on the skin and reach to the lesion, restoring the kidneys.

◆ What will you expect from Medicated Bath?

Alleviate the symptoms of end-stage renal disease. With medicated bath, the symptoms of chronic kidney disease can be alleviated especially fatigue and swelling.

It is more effective in chronic renal insufficient than in end-stage renal failure patients.

It has a unique curative effect on the itching skin.


It regulates the immune system and improve the immunity and self-healing.

Causes of Bilateral Polycystic Kidney Disease

Polycystic Kidney Disease is a kind of hereditary Kidney Disease with great damage, and frequently related to bilateral kidneys. Besides hereditary factors, there are still some other factors that can cause Polycystic Kidney Disease.
Epithelial cells of renal tubule and cells on cyst wall can be changed by cyst gene, which can cause the following results:

Ⅰ. Cyst gene can affect Na-K-ATPase of tubule epithelial cells, which can increase inner fluid of renal tubule and make cells on cyst wall secrete fluid.
Ⅱ. Epithelial cells of renal tubule proliferate continuously, forming polypoid lesion which can cause renal tubule obstruction, and the obstruction can lead to fluid retention which can bulge tubule, and then cysts form.

Ⅲ. Infections and toxin can act on renal tubule, which can activate cyst gene and change tubule cells metabolism, or even cause epithelial cells apoptosis. Apoptosis cells can also lead to obstruction after they slough off.

Ⅳ.Epithelial cells can secrete series of bioactive substances which can increase cyst fluid secretion.

Ⅴ. Cyst gene can lead to abnormal Extracellular Matrix and change the condition of basement membrane and tubule wall, which can provide a favorable environment for cyst growth.

Micro-Chinese Medicine is a distinctive Chinese Medicine Treatment, which can treat the disease from its primary cause, namely Renal Fibrosis. It mainly treats this disease by the following methods.

Firstly, Micro-Chinese Medicine takes the medication way of micronized Chinese Medicine combined with external osmosis on renal area. Smashing and decoction are adopted in the process of Traditional Chinese Medicine Treatment. While our hospital takes high-technology to micronize medicine into more refined powder.
Through this method, medicine can be absorbed easily. Besides, active substances of Chinese Medicine can be sent into renal lesion directly by the method of external osmosis on renal area, which can get a higher medicine utilization rate.


Secondly, mainly depending on Micro-Chinese Medicine and puting Western Medicine in a supportive role is the treatment principle that our hospital insists. As for PKD patients who suffer from Hypertension and Anemia, they need take Western Medicine to control their symptoms in order to make Micro-Chinese Medicine play a more effective role in recovering renal inherent cells and inhibiting secretion of cyst fluid.

Routine Treatment of Polycystic Kidney Disease

Polycystic Kidney Disease is a kind of terrible hereditary disease. It causes damage to renal parenchyma, and then renal function abnormality happens. When kidney lost their function of eliminating body wastes, Uremia which is a threat to human life appears due to toxin accumulation in human body.

Many treatments can be used to treat Polycystic Kidney Disease. Among these treatment methods, Western Medicine treatment is an adjutant treatment of operation. As for Western Medicine Treatment, it usually treats the disease starting with treating symptoms. For example, relevant antibiotics are used to deal with Haematuria and complicated infection; hypotensor is taken to reduce High Blood Pressure and related medicines are used to decrease creatinine and urea nitrogen.

Some routine treatments of Polycystic Kidney Disease can be listed as follows:
Firstly, dialysis and Kidney Transplantation. Dialysis, especially Hemodialysis, should be taken timely if illness condition develops into End Stage Renal Failure. Surviving rate of Kidney Transplantation is some equal to other operation, but due to complicated disease, problem of post-operation can be difficult to solve, which can affect operative effect.

Secondly, operation. Operation is a normal treatment of Polycystic Kidney Disease, with the purpose of removing big cysts by surgical operation. With big cysts being removed, more space is left for smaller cysts. When smaller cysts grow up, they can compress kidney again. This treatment method can not recover Polycystic Kidney Disease. What’s more, it brings new injury to patients’ body and spirit. Symptoms of most PKD patients appear again about 6 months after operation, and illness condition can be worse than before with rapid aggravated renal function.

Thirdly, infections that happen to renal parenchyma and inner cyst are main complications of PKD, and combined complication of antibiotic is used to deal with them.


Fourthly, treating High Blood Pressure. Activation of renal ischemia and renin-angiotensin-aldosterone system is main reason of High Blood Pressure, and hypotensor is taken on this basis.

Treatment for Childhood Polycystic Kidney Disease

Childhood Polycystic Kidney is a kind of children’s hereditary nephropathy. In the past, Childhood Polycystic Kidney patients generally couldn’t survive to adulthood because there is no effective treatment. And many pregnant women terminate pregnancy helplessly if fetus is diagnosed as Childhood Polycystic Kidney patient. Also some pregnant women terminate pregnancy without any hesitation after knowing that they are suffering from Polycystic Kidney Disease, due to heredity of Polycystic Kidney.

General treatment method for Childhood Polycystic Kidney is Puncture operation of Western Medicine. But illness condition is easy to relapse with series of complications after this operation. What's more, it can’t treat disease fundamentally, only treating symptoms instead of disease.

Shijiazhuang Kidney Disease Hospital developed Micro-Chinese Medicine Osmotherapy after many years of clinical practice and research. The treatment mechanism is that the progress of kidney fibrosis is blocked by dilating blood vessels, anti-inflammation, anticoagulation, anti-viscosity, degrading fibrosis material and so on. Through this way, impaired renal inherent cells and function can be repaired, and renal structure can be recovered.


The treatment method of Micro Chinese Medicine Osmotherapy in Shijiazhuang Kidney Disease Hospital is promoting blood circulation on cyst wall and improving permeability of cyst wall qualitatively, in order to make sac liquid be reabsorb and reduced continuously, even no longer secrete. Cysts shrink accordingly until to smallest condition with cystic internal pressure reducing, which completely removes cysts’ oppression on normal tissues surrounding kidney. In this way, renal function recovers gradually and symptoms are relieved thoroughly.

Complications of Polycystic Kidney Disease

Bleeding may happen to internal cysts of Polycystic Kidney Disease patients, and patients may feel grievous painful if bleeding happens in a sudden. Bleeding may be caused by complicated cancer on cyst wall. Therefore, besides treating Polycystic Kidney Disease actively, taking proper and timely treatment to cure complications is also important. Main complications of Polycystic Kidney Disease patients can be listed as followed:

Firstly, Kidney Stone and internal kidney calcification: When patients get a stronger pain, colic or gross Haematuria, they may have the possibility of suffering Kidney Stones.

Secondly, urinary tract infection: complications of Polycystic Kidney Disease include cystitis, nephropyelitis, cyst infection and abscess around kidney. If Leukocyte Cylindruria and rapid response to routine anti-inflammatory treatment happen among complications of PKD, it is beneficial to diagnose nephropyelitis. While positive hemoculture and local pressing pain mostly refer to cyst infection. Infectious cysts can be found through CT examination.

Thirdly, cyst cancerization: whether cysts can turn to caner or not is still disputed. If patients suffer from complications of PKD get pain on renal region or Haematuria change, and they have a losing weight and increasing blood deposit as well as anemia not equal to kidney function or globalism, patients should be cautious of complicated renal cancer. At this moment, patients should receive CT examination in time, and renoarteriography can be taken if necessary.

If cysts of PKD patients is located at low position of kidney and very close to ureter, complications of PKD patients can worsen hydronephros. And pressure caused by urine on renal pelvis can cause pain on back. Besides, this can lead to renal infection.


PKD patients should receive effective treatment actively in order to prevent complications happening. Micro-Chinese Medicine Osmotherapy has a good therapeutic effect on treating PKD. It avoids liver injury caused by gastrointestinal tract stimulation from oral medicine. During the process of Micro-Chinese Medicine treating OKD, Chinese Medicine can arrive at renal lesion directly and local high medicine concentration can play a more effective role in treating this disease. Through this method, cyst fluid can be recycled more quickly, which can reduce cyst size and cystic pressure on kidney as well as relieve renal injury. Besides, Micro-Chinese Medicine can protect remained healthy nephron and repair renal function gradually. Meanwhile, some Western Medicine can be taken to prevent inflammation, which can offer a beneficial environment for Chinese Medicine to play its function fully. What’s more, Micro-Chinese Medicine has no side effect with less recurrence.

What Is The Standard of PKD Diagnosis

What is the standard of PKD diagnosis? Here is a brief introduction of Adult PKD which refers to autosomal dominant inheritance PKD.

Ⅰ. Familial history.

Ⅱ. Clinical symptoms

Firstly, symptoms of urinary system: most patients do not have symptoms until they get around 40 years old. They can get pain on waist and back or renal colic. Symptoms of Haematuria, upper urinary tract infection and complicated Kidney Stone appear, or even symptoms of Chronic Renal Failure, like headache, nausea, vomiting as well as tiredness and weight loss can be found.

Secondly, symptoms of cardiovascular system: High Blood Pressure usually happens as one of the primary symptoms, complicated with left ventricular hypertrophy, mitral valve prolapse, aortic insufficiency as well as intracranial aneurysm and other diseases.

Thirdly, symptoms of digestive system: 30% to 40% PKD patients accompany with liver cyst and 10% PKD patients get pancreatic cyst. While about 5% patients may have spleen cyst at the same time.

Ⅲ. Body Check

Patients can be found unilateral or bilateral kidneys with nodular condition when touched. Pressing pain can be felt if there is a infection. 50% patients have increased waist size.

Ⅳ. Assistant Test.

Firstly, routine urine test: there is no abnormality in urine test in the early stage of PKD. Microscopic Haematuria can be found in middle and late stage of this disease,and some patients may get Albuminuria. White Blood Cells and pyocyte can be found if there is a complicated Stone or infection.

Secondly, test on urine osmotic pressure: even there is only a few cysts in early stage of pathological change, manifestation of renal concentrated function injury can be found, showing that this change in not related with renal structure damage only, it may be related with renal adverse reaction to anti-diuretic hormone. Under such circumstance, renal concentrated function declines before glomerular filtrating rate decrease.

Thirdly, serum creatinine is increasing with the loss of renal compensatory ability. Creatinine clearance rate is a sensitive index in this condition.
Fourthly, plain film of KUB shows enlarged kidney image with irregular shape.
Fifth, IVP shows deformation of renal pelvis and renal calices caused by cystic pressure. Renal pelvis and renal calices can be in a shape of spider. Renal calices is wide and plain with thin and stretched calices neck.

Sixth, through Type-B Ultrasonic examination, a larger amount of shadow area can be found in kidney region.


Seventh, through CT examination, bilateral kidneys enlargement can be found with thin cysts filled with cyst fluid.

How to Treat Complications of PKD Patients

With cysts growing, PKD patients can get a series of complications which can worsen illness condition further. For this reason, treating complications of PKD is especially important.

PKD is a kind of hereditary disease, with cysts with various sizes spreading the whole kidney. These cysts grow with age, which can compress healthy kidneys and damage renal structure, reducing nephron numbers that can secrete urine. With time going, kidney is so injured that it can not maintain human normal life, and then Uremia appear.

Main complications of PKD are High Blood Pressure, Haematuria, kidney enlargement and urinary tract infection. Waist pain and fever can be found if cysts are bleeding. Patients may get aching pain if Uronephrosis happen, and colic and Haematuria can be found if there is complicated Stone. If effective treatment can not be taken in time, with illness condition worsening, end stage PKD patients can only depend on Dialysis to maintain life.

The root cause of complications of PKD patients is growing cysts, so complications of PKD patients should be treated starting with shrinking cysts. Western Medicine can be taken to treat related symptoms, while Chinese Medicine should be taken to treat this disease from its root which means that inhibiting cysts growing tendency. Chinese Medicine can eliminate activities of cystic epithelial cells and prevent them secreting cyst fluid. Therefore, cysts can stay in this stage and stop growing.

However, we can not let existing cysts stay there forever. So proper medicine should be taken to increase permeability of cyst wall and recycle cyst fluid, excreting these fluids out of body with urine. This is treating cysts from its primary cause. After healing, this disease seldom relapses.


Inhibiting cysts growing and shrinking developed cysts can control this disease effectively. Complications of PKD patients can also be controlled effectively, because root cause—cysts, is removed.

Case Analysis of Polycystic Kidney Disease

Patient: Zhou Huadie
Gender: female
Age：54
Province: Henan Province
Main cause: patient got tiredness and pain on abdomen for 4 months.
Diagnosis: Polycystic Kidney Disease ,Chronic Renal Insufficiency Decompensatory Period

Hospitalization: April, 2008

Patient’s illness condition when she went to our hospital: high blood pressure, blood routine test shows normally, light acidosis, serum creatinine 445umol/L, BUN12.9mmol/L，routine urine test shows: PRO(+)BUN(+), Urine Protein Content: 0.29g/24h, bilateral abdomen swelling and painful sometimes.;Type-B Ultrasonic result: left kidney 19.0*7.3cm, right kidney 20.5*6cm.

Treatment: Micro-Chinese Medicine Osmotherapy was taken after patient hospitalized.

Re-examination result after patient received Micro-Chinese Medicine Osmotherapy: serum creatinine: 155umol/L，BUN11.2mmol/L，routine urine test: PRO(-)BUN(-), Urine Protein Content: 0.16g/24h, B ultrasound shows: left kidney 14.1*6.0cm, right kidney14.8*5.5 cm. Size of bilateral kidneys reduce obviously; patient is full of vitality, and abdominal pain seldom happens.


Expert Comment: Polycystic Kidney Disease is a kind of autosomal dominant hereditary disease. Either of parents suffer from PKD, each of their children may get this disease at a risk of 50% Generally, disease develops quickly after patients get to 40 years old. Main symptoms, like high Blood pressure, occult blood and protein in urine, abdominal pain, with masses or abdominal distention, appear. Patients with kidney damage can have a high serum creatinine. Patients who suffer from serious illness condition have symptoms of nausea, vomiting. If patients' illness condition can not be controlled well, it will develop into Uremia. Micro-Chinese Medicine can improve blood circulation, and absorb cyst fluid and excrete fluid out of body with urine, which can shrink cyst, relieve the cystic pressure on normal renal tissues and improve renal ability of excreting toxin. Then toxin in body can be decreased and patients can get rid of dialysis.

Diet Principle for Polycystic Kidney Disease Patients in Spring

Spring is a season with more wind and extreme dry weather. In this time, patients should pay high attention on diet in order to avoid worsening illness condition or cause recurrence. In spring, the following points should be noted to PKD patients.

Polluted food is easy to cause gastrointestinal disease or even poisoning which can threaten life. Therefore, patients should pay more attention on food cleanness, trying to avoid eating food outside, especially food of street stalls.
Meal amount is also limited for PKD patients. For example, if patients eat too less, they can suffer from malnutrition, while too much food intake can be easily damage digestive function of spleen and stomach, causing obstruction in blood and Qi. Therefore, patients should have a proper diet in order to keep necessary energy and nutrition.

PKD patients should have a diet with low salt and low fat. Spicy food, beef, mutton and animal viscera should be avoided. More fresh vegetable and fruits are beneficial for patients’ health. Patients should check their renal function regularly in order to prevent renal injury.

PKD patients should avoid cold and uncooked food which can injure Yang. Patients should take a proper diet according to their illness condition.

Basically, PKD patients should have a light diet with low protein. Besides, water intake should also be limited in order to prevent night urine retention.


Besides diet, PKD patients should also have a proper rest and avoid tiredness.

Complications of Adult Polycystic Kidney Disease

Polycystic Kidney Disease is a kind of hereditary Kidney Disease. Once cysts grow bigger, they will compress kidneys and lead to damage to kidneys, causing a series of complications.

Firstly, Nephropyelitis: it is a common complication of Polycystic Kidney Disease. Patients may have no symptoms sometimes, and there is very little or even no pyocyte in urine.

Secondly, cyst infection: it can cause pain and pressing pain on kidney region. Patients may also have symptoms of fever.

Thirdly, Haematuria: seldom cases can have symptom of active and continuous gross Haematuria which may threaten patients’ life.

Prognosis and prevention of Adult Polycystic Kidney Disease: patients who get clinical symptoms of PKD at 35 to 40 years old can have a relative better prognosis.


Micro-Chinese Medicine Osmotherapy can treat PKD effectively through dilating blood vessel, activating renal blood circulation and protect remained healthy nephron. Active substances of Chinese Medicine can arrive at renal lesion directly, which can make medicine play maximum function. Then injured kidney can be repaired and renal function can be recovered gradually.

Pathogenesis of Polycystic Kidney Disease

Polycystic Kidney Disease is a kind of hereditary Kidney Disease that many cysts grow in renal cortex and renal medulla, with characteristic of familial aggregation. So many reasons can cause Polycystic Kidney Disease, including congenital hereditary factors and acquired factors.

Ⅰ. Congenital factors of Polycystic Kidney Disease:

Firstly, congenital dysplasia is one of the causes of Polycystic Kidney Disease. Congenital dysplasia can cause many diseases. As for cystic Kidney Disease, it may cause sponge kidney, dysplasia Polycystic Kidney Disease and other Kidney Diseases. Gene of congenital dysplasia patients is generally normal. So it is different from gene inheritance and gene mutation.

Secondly, gene mutation: as for Polycystic Kidney Disease, most patients are inherited this disease from their parents gene, divided into Autosomal Dominant Polycystic Kidney Disease and Autosomal Recessive Polycystic Kidney Disease. However, some patients get PKD neither from inheritance nor from congenital dysplasia. They get the disease due to gene mutation in embryo forming stage. During this stage, due to various factors, gene mutation happens, causing Polycystic Kidney Disease. Through this condition seldom happens, it still has the possibility. Therefore, some PKD patients may not have hereditary history.

Ⅱ. Acquired factors of Polycystic Kidney Disease

Firstly, various infections: infections can cause abnormal change to organ internal environment, which is beneficial for cystic gene mutation to happen. Then activity of cysts internal factors increases, promoting cysts formation. Besides, infections on any part of body can get into kidney with blood, affecting cysts growth. If cysts were infected, besides clinical symptoms aggravation, it can speed up cysts growing rate and damage renal function further. Common infections include upper respiratory tract infection, urinary tract infection, gastrointestinal infection, skin infection, trauma infection and apparatus infection, etc. it means that both bacterial infection and virus infection can affect cysts greatly.

Secondly, toxin: toxin accumulated in body can damage various cellular organic tissue, resulting in disease happening or even threat to life. Besides, toxin is also one of the main reasons of gene mutation and congenital dysplasia. Some common toxins include agricultural chemicals, some chemical agents, radiation as well as pollution and so on. In addition, some medicines are nephrotoxic. These medicines can cause renal injury if they are used improperly.


Because Polycystic Kidney Disease is the interaction of congenital and acquired factors, we can control acquired factors actively on the condition that congenital factors can not be changed. Patients should pay more attention on daily living regulation and diet in order to prevent Polycystic Kidney Disease happening.

Main Complications of Polycystic Kidney Disease

Ⅰ. Pain on kidney region is the main symptom of PKD. Patients always have a feeling of pain or pressure on waist and back. Pain can be worsened after physical activity, long-time walking or sitting. Painful feeling can be relieved after a bed rest. Besides, kidney internal bleeding, stone movements or infections can also cause serious pain.

Ⅱ. Haematuria: about 50% patients get microscopic Haematuria, and sometimes gross Haematuria can be found. This is caused by blood vessel rupture of cyst wall. Blood coagulated in ureter can lead to colic. Besides, Haematuria usually happens accompanied with Leucocyturia and Albuminuria. Protein in urine is tiny, not more than 1.0g per day. When there is kidney internal infection, obvious pyuria appears with worsening Haematuria as well as pain on waist accompanied by fever.

Ⅲ. High Blood Pressure is common among Adult Polycystic Kidney Disease. 50% patients suffer from High Blood Pressure before serum creatinine increase, which is related with cystic pressure on surrounding tissue as well as activation of Renin-Angiotensin-Aldosterone system. It has been proved that cyst growing has a close relationship with High Blood Pressure. Besides, patients who suffer from High Blood Pressure may have more rapidly growing cysts, which can affect prognosis directly.

Ⅳ. Renal Insufficiency: it is inevitable that Renal Insufficiency appears in PKD. Very few patients get Renal Failure in teenager period. Normally, seldom Renal Function decline appear before patients are 40 years old, and half renal function can be kept for 50% patients when they are 70 years old. However, the course of illness developing into Renal Failure is much shorter if patients suffer from High Blood Pressure.

Ⅴ. Polycystic Liver Disease: as for patients who suffer from PKD from middle age, about half of these patients may get Polycystic Liver Disease at the same time, and this proportion increases to 70% after patients get 60 years old. Generally, Polycystic Liver has a slow development and it is usually found about 10 years later than PKD. Cysts of Polycystic Liver Disease are caused by expending of bile duct. Besides, pancreas and ovary can also have cystic change.

Ⅵ. Kidney Enlargement: there is an unequal pathological change of bilateral kidneys. Kidneys may occupy the whole abdominal cavity. Large amount of cysts grow on kidney surface, which leads to irregular kidney shape.


Ⅶ. Angeioma of circle of Willis: 10% to 40% patients may get this complication which is usually found in a further check of cerebral hemorrhage caused by angeioma rupture. Besides, thoracic aortic aneurysm and cardiovalvular diseases like valvular inadequacy and prolapse are also common.

How to Prevent Renal Failure in Polycystic Kidney Disease

Polycystic Kidney Disease is a kind of congenital hereditary disease, mainly expressed by various sized cysts in bilateral kidneys, which can enlarge kidney obviously and cause shape abnormality to kidneys. With illness development, cysts grow bigger and more and finally Renal Functional Failure appears due to great damage of renal tissue. Well then, how to preventing Renal Failure happening in the course of PKD.

Firstly, discover illness condition as early as possible. PKD has a hereditary tendency, with equal incidence to both male and female. For this reason, there may be several family members suffering from PKD at the same time in a family with PKD history. PKD always happens among patients who are at middle age. Even some patients do not realize this disease until symptoms of Renal Function Failure appear.

Secondly, preventing and treating complications early. High Blood Pressure, urinary tract infection and cyst rupture are common among complications of PKD. Meantime, these complications are also significant factors inducing and worsening renal function damage. Therefore, these complications should be treated and controlled in time. When choosing medicine, patients should be care about nephrotoxic medicine.

Thirdly, Chinese Medicine treatment: Chinese Medicine has a good effect on treating Chronic Renal Function Failure, especially on treating early or middle stage patients. Chinese Medicine can improve patients’ clinical condition obviously and control illness development as well as reduce serum creatinine and urea nitrogen.

Fourthly, family care and nursing: Renal Function Failure of PKD is a kind of chronic progressive developing disease. It may be worsened by mood swings, extreme tiredness or improper diet as well as trauma and other related factors. Therefore, patients should keep a happy mood and adjust their work and rest properly as well as build confidence to overcome this disease and cooperate with treatment actively. As for diet principle, patients should take a light and fresh diet with rich nutrition. More fruit is OK. Besides, patients should limit their protein intake properly and avoid icy, uncooked and spicy food. Cigarette and alcohol are forbidden. If patients suffer from serious Hypertensive Edema, they should limited sodium salt intake. in addition, patients should take some exercise, but be cautious about compress on waist and abdomen in order to prevent cysts rupture. Patients suffering from serious illness condition should take a bed rest.


Fifthly, Kidney Replacement Therapy: due to renal function decline seriously, patients who are in late stage Renal Function Failure of PKD usually have a really bad reaction to medicine. Besides, these patients’ clinical symptoms worsen gradually and illness condition is so dangerous that Kidney Replacement Therapy, Hemodialysis or peritoneal dialysis, should be considered. Abdominal cavity reduces because patients’ kidneys enlarge obviously. Under such circumstances, peritoneal dialysis nearly has no effect, so hemodialysis is taken normally. As for patients with continuous bleeding or uncontrolled blood pressure, surgery operation can be considered to remove kidney. Kidney Transplant can be taken if possible.

Can Polycystic Kidney Disease Take Exercise

Can Polycystic Kidney Disease take exercise? This is a puzzling problem for PKD patients. According to this problem, specialists on Kidney Disease notice that PKD patients can take physical exercise properly and scientifically, but excessive exercise is forbidden. As for PKD patients, which standard of daily exercise and work can not affect their body health? Normally, this depends on patients’ individual illness condition. Generally speaking, there are very few problems before patients are 30 years old. Though cysts of most PKD patients begin to compress each other, the pressure caused by cysts is tiny in this period. So patients can take some safe exercise at this moment, but crashing exercise like basketball should be avoided. Usual light exercise can not affect kidneys normally.

If patients are about 40 years old, they should pay more attention on daily work and life. Because cysts produce larger pressure in this period and strenuous exercise usually bring cyst rupture to patients. For this reason, patients should avoid pressure or collision on kidney region. Especially for a housewife, they should be more cautious when she is looking after a baby in order to prevent baby kicking her kidney region.

As for patients who had suffered from Haematuria before, they are required to pay more attention on their daily activity, because cysts of these patients are much easier to get cyst rupture. In order to prevent Haematuria recurrence, patients should take some exercise with less bending angle and lighter strength burn. Besides, these patients should take chairs with similar height of their knee when they are sitting. Walking and slow run can be taken as main morning exercise.


In a word, PKD patients who want to take some exercise should take a proper exercise volume and avoid excessive activity. Besides, the most important thing is to treat PKD in time and control cysts growing. Only in this way, PKD patients can have a normal life as other healthy person.

Immunotherapy to Treat Polycystic Kidney Disease

With deep research on PKD treatment, scientists has made a new break—Immunotherapy. Before learning more about Immunotherapy of treating PKD, the first thing should be done is to know what is Polycystic Kidney Disease and how does it occur.

Immunotherapy treats PKD starting with recovering and renewing injured renal cells. When cysts are still small, they seldom cause damage to renal parenchyma. But with cysts growing, they will compress surrounding renal tissue and renal blood vessel, which can lead to renal local microcirculation obstruction, causing renal ischemia and anoxia. These can damage endothelial cells of renal capillary and attract inflammatory cells infiltration in blood circulation, which speed up renal function injury and start the process of Renal Fibrous. Besides, mechanocyte distributing in renal interstitium can turn into myofibroblast which can secrete and synthesize Extracellular Matrix (ECM) and immune complex. These ECM and immune complex are not easy to de degraded. For this reason, there is an unbalance between ECM degradation and ECM synthesis. Massive ECM deposit in kidney, which causes glomerular sclerosis and renal tubular atrophy. Therefore, renal fibrous tissue will replace healthy nephron gradually. With renal function decline more and more, renal function disappear completely, which means that PKD has developed into end stage. At this moment, patients get Renal Failure or Uremia.

Immunotherapy is a kind of cell with characteristics of multi-directional differentiation and self-replication. Immunotherapy can distinguish injured renal inherent cells and recover these injured cells after they entering into kidney lesion. Besides, Immunotherapy can also produce various types of inherent cells, which can relieve the condition of renal ischemia and anoxia and promote blood circulation of cyst surface. All these methods are helpful to recycle cyst fluid. Besides, Immunotherapy can also inhibit cystic cells growing, which can shrink cysts gradually. Once renal inherent cells are repaired, they can play their function on degrading immune complex and ECM, achieving a balance between ECM synthesis and ECM degradation. Therefore, renal function recovers gradually.


Though Polycystic Kidney Disease is a kind of hereditary disease, it is not so terrible. Patients should cooperate with doctors actively. Beside, patients should pay more attention on daily diet and exercise. Regular examination is required in order to find this disease and take effective treatment as early as possible.

Mental Care of Polycystic Kidney Disease Patients

Polycystic Kidney Disease should pay more attention on mental care. But why? Actually, one person’s mental condition has great influence on occurrence, development and treatment of Kidney Disease. Different mental characteristics can lead to functional disorder of internal organ and worsen Kidney Disease directly or indirectly.

In Chinese Medicine Therapy, mental factor is one of pathogenetic factors. Human body is a closely integrated organic whole. One person’s mentality is closely related with internal organic function. During the process of Kidney Disease development, mentality is also very important. A good mental mood is beneficial to make Qi flow smoothly, which is helpful to keep each internal organ operating normally. Then water metabolism as well as secretion and excretion function can be normal. All these are favorable for Kidney Disease patients to recover.
Contrarily, bad mental mood can cause Qi dysfunction and blood circulation disorder,, resulting in functional disorder of internal organs which can cause or worsen illness condition.


Clinically, most PKD patients will lose confidence of overcoming the disease due to much long disease course or worsening illness condition. They may feel despondent and pessimistic, or even despairing. For this reason, other family members or patients friends should console patients frequently and encourage patients to fight against with disease. Through this way, patients can cooperate with doctors actively in a favorable mood. During the process of treating this disease, patients should avoid bad mental stimulation, which is helpful for patients’ recovery.

Case Analysis of Polycystic Kidney Disease and Polycystic Liver Disease

Patient Name: Zhang Chunzhi

Gender: female

Age: 62 years old

Province: Handan, Hebei Province

Diagnosis: Polycystic Kidney Disease, Polycystic Liver Disease

Main cause: patient has suffered from Polycystic Kidney Disease and Polycystic Liver Disease for more than 20 years. Bilateral kidneys are both larger than 20cm. Patient herself can touch enlarged kidney. Urine amount: 800ml with light color. Serum creatinine: 872 umol/L. BUN: 34.2mmol/L.

Treatment: after 26-day treatment in Shijiazhuang Kidney Disease Hospital, patient showed great sensitivity on micronized Chinese Medicine. She said that kidneys she has touched are not as hard and large as before.

Test result: serum creatinine, 264umol/L; BUN: 12.3mmol/L. This result is really a great surprise for patient herself and her attending doctor.


Expert comments: PKD is one of common causes of Uremia. Continuously growing cysts can compress healthy nephron, causing nephron injury. Then Renal Insufficiency occurs. According to the above, Shijiazhuang Kidney Disease Hospital adopts Micro-Chinese Medicine to treat Polycystic Kidney Disease. Micro-Chinese Medicine can permeate into cysts directly, and fully play the role of activating blood and dredging channels, eliminating blood stasis and removing obstructions in blood vessel. All these are beneficial for kidney to excrete cyst fluid. Therefore, cyst internal pressure can be reduced and cyst size can be smaller with gradually recovered renal function. As a result, creatinine and urea nitrogen decrease.

Normal Treatment of Adult Polycystic Kidney Disease

Adult Polycystic Kidney Disease is a kind of congenital hereditary Kidney Disease, belonging to autosomal dominant inheritance disease, which means that this disease can inherit from generation to generation, but never skip generation. Each parent suffer from Polycystic Kidney Disease, each of their children can have 50% possibility of getting this disease. According to statistics, one in 400 to 1000 persons can suffer from Polycystic Kidney Disease.
With PKD occurring, clinical complications, cyst rupture, bleeding, inflammation and stones, appear. All these complications are expressed on patients’ body, which can decrease patients’ immunity and cause infection easily.

Generally, cyst decortication and puncture sclerotherapy are used to treat Polycystic Kidney Disease. These two operations can relieve symptoms of abdominal distension and waist pain in a short time, but other complications of Haematuria, anemia, High Blood Pressure and high creatinine can not be solved completely.
Such operations can only treat symptoms instead of treating the disease itself, which can aggravate kidney condition and cause renal ischemia and anoxia as well as glomerular low perfusion. Then patients’ renal function declines gradually and renal ability of excreting toxin decreases greatly, expressed by continuously high serum creatinine. Finally PKD develops into Uremia.

The correct way of treating Polycystic Kidney Disease is to start with recovering patients’ injured renal function and treating complications at the same time. Only in this way, PKD can be treated effectively.


As last, one point should be noted that patients should avoid any exercise that may increase cyst internal pressure; no matter they are accepting treatment in hospital or receiving consolidation treatment at home.

Chronic Waist Pain of Polycystic Kidney Disease Patients

Chronic waist pain which is a common symptom of Kidney Disease should not be neglected by patients. Especially for patients suffering from Polycystic Kidney Disease, they should pay much more attention on waist pain than others, because the painful feeling may be caused by urinary tract infection or Kidney Stone caused by growing cysts, or even renal cell carcinoma can be one of the causes. Patients who suffer from light pain may feel abdominal swelling and discomfort, while patients with serious condition may feel seriously painful. Such pain can be worsened after strenuous exercise. Waist pain may be caused by pressure on renal parenchyma or renal hilus resulting from growing and increasing cysts. Sharp pain always refers to complications of Kidney Stone, hematomas or obstruction caused by renal bleeding, infections and malignant tumor, etc.

Different Polycystic Kidney Disease patients have pain of different degrees, and mental factors can aggravate waist pain of 40% patients. As for patients who suffer from waist pain mainly caused by mental factors, they should accept a systemic treatment, including mental relaxing training and distracting attention, etc. Presently, psychotherapy has been more researched, because it can avoid some danger from taking medicine.

Polycystic Kidney Disease Complicated with Stone

Patient: Wu Changwei, Male, 60 years old

Diagnosis: Polycystic Kidney Disease complicated with Multiple Stone, Chronic Renal Insufficiency Compensatory Stage

Hospitalization: 22ed Jan, 2007 to 6th Feb, 2007

Main Cause: patient has suffered from intermittent waist pain for 15 years.
Test when patient went to hospital: 1. Polycystic Liver Disease; 2. Polycystic Kidney Disease; Type-B Ultrasonic result: left kidney, 22.9*9.6cm; right kidney, 17.1*9.0cm’ large cyst in left kidney, 7.8*5.8cm; large cyst in right kidney, 5.4*4.6cm; small stone can be found in cysts.

Renal Function Test: serum creatinine, 135.7umol/L; endogenous creatinine clearance, 51.5ml/min

Morse Test: renal tubular concentrating and dilution functions are damaged. Patient has symptoms of waist pain and Haematuria.

Treatment: Micro-Chinese Medicine is taken to anticoagulation, antioxidant, anti-inflammation and active blood circulation in order to protect renal function. After 10-day treatment, patient’s appetite increases and waist pain reduced gradually. Brick red granular deposite is found in urine.


Expert Comment: with cysts growing and increasing, these cysts will compress healthy normal renal tissue, causing renal ischemia and anoxia. Then renal function and renal ability of excreting toxin decline. Micro-Chinese Medicine can improve renal blood circulation and shrink cysts through methods of activating blood and dredging channels, eliminating stasis and removing obstructions in blood vessel, repairing and renewing. Through these methods, renal function can be improved, so does renal ability of excreting toxin. Besides, with cyst internal pressure reducing, the pressure on gastrointestinal tract decreases, which is helpful to improve digestive function, then abdominal discomfort can be relieved.

Details of Renal Function Tests

When patients are doubted to have renal injury or they have diagnosed as Kidney Disease, they are always required to receive renal function tests. So what does renal function tests test for indeed? Kidney is a very important organ with the function of excreting water, metabolic waste, toxin and medicine, reserving necessary substances for human body in order to maintain the balance of water, electrolyte as well as acid and base. Besides, kidney still has the function of internal secretion like synthesis and secreting renin and erythropoietin. Based on the above, renal function tests mainly test these functions of serum creatinine, urea nitrogen, internal creatinine clearance and serum uric acid, etc.

Firstly, Blood Uria Nitrogen (BUN) tests: there are more than 15 kinds of non-protein nitrogen in blood, and urea is the most, occupying about 50%. Then amino acid, uric acid, creatinine, creatine and nitrogen follow after. Urea is the final production of protein metabolism, synthesized in liver and transported to kidney through blood circulation. Then urea is excreted out of human body after glomerular filtration. When renal parenchyma is injured, glomerular filtrating rate also decreases at the same time, which can increase urea concentration of blood. For this reason, Blood Uria Nitrogen can be taken as a reflecting index of glomerular filtrating rate.

Secondly, serum creatinine tests: serum creatinine can be divided into endogenous creatinine and exogenous creatinine. Generally, per 20g muscle metabolizes 1mg creatinine per day. If people do not take strenuous exercise, endogenous creatinine secretion is steady every day. Serum creatinine is excreted out of human body after glomerular filtration, and renal tubule seldom reabsorb creatinine with less excretion. Under the condition of controlling exogenous creatinine intake, concentration of serum creatinine mainly depends on glomerular filtration. Therefore, concentration of serum creatinine is a reflection of glomerular filtrating function.

Thirdly, creatinine clearance rate test: plasma liquid amount filtrated by glomerulus per unit time is called glomerular filtrating rate (GFR). Main function of glomerulus is filtrating function, while the objective index of glomerular filtrating function is GFR. In per unit time, the amount of cleared endogenous creatinine of some certain volume plasma is called endogenous creatinine clearance rate. After filtrated by glomerulus, creatinine is difficult to be absorbed and excreted by renal tubule. So under the condition of strictly limiting diet and muscle activity, endogenous creatinine clearance rate should be some equal to GFR. For this reason, this test is a relative effective way to test glomerular filtrating function.

Fourthly, serum uric acid (UA) test: uric acid is the final production of purine metabolism in human body. Nucleic acid of food can be decomposed into purine, while nucleic acid in organic tissue can be decomposed into purine nucleoside. Both purine and purine nucleoside can produce uric acid after the process of hydrolysis, deamination and oxidization. Besides small part uric acid can be broke up in liver, most of uric acid is excreted out of body by kidney. All uric acid is filtrated by glomerulus, and 98% to 100% is reabsorbed by near-end glomerulus. So in normal condition, uric clearance rate is really low, which means that kidney can excrete creatinine easily but excrete uric acid difficultly. In early stage Kidney Disease, uric acid concentration increases firstly. This is beneficial to make an early diagnosis of renal injury.


Because kidney has so many functions and strong reservation ability, even the most sensitive test methods can not test out early and light renal injury. Besides, test result can be influenced by Heart Disease, Anemia and other non-Kidney Disease. Therefore, judgement of renal function can not be made only depending on some single test result. An exact diagnosis should also depend on comprehensive analysis of clinical symptoms.

Hypertension of Polycystic Kidney Disease (PKD)

Polycystic Kidney Disease (PKD) belongs to hereditary Kidney Disease, kind of congenital abnormality. Cysts of Polycystic Kidney Disease (PKD) are mainly caused by eccyliosis of renal parenchyma and renal structure, with different involvement of each kidney. These cysts compress surrounding healthy renal tissue, which can cause renal ischemia and anoxia as well as low renal perfusion. Then Hypertension of Polycystic Kidney Disease (PKD) happens, which means that Polycystic Kidney Disease (PKD) patients begin to suffer from Hypertension.

Through observation, many grapelike cysts with different sizes spread over the whole renal tissue, and the volume of cysts is much larger than the volume of renal parenchyma. Kidney enlarges obviously and light yellow liquid can be found in cyst at kidney section. Due to internal bleeding, liquid color may be red or brown, contenting tiny protein, chloride, cholesterin and light urea. Cysts may be open to each other, but isolated with renal pelvis. Cystic pressure on renal tissue can cause renal tubule atrophy and sclerosis, damage glomerulus and renal function. Besides, these cysts also compress kidney blood vessels, reducing local blood flow. Therefore, there will be a high concentration of angiotensin with shrunk blood vessel, leading to Hypertension. In some degree, it is a vicious circle between Hypertension and renal function injury.


Based on the above, generally, once Polycystic Kidney Disease (PKD) patients get Hypertension, it means that renal function is about to decline or has already been damaged. For this reason, patients should pay more attention on controlling Hypertension.

Advantages of Micro-Chinese Medicine in Treating Polycystic Kidney Disease

Polycystic Kidney Disease which has a long and complex disease course is not easy to be treated completely. Western Medicine Treatment can only treat this disease starting with single cyst, which can not treat this disease radically, having less therapeutic effect. Traditional Chinese Medicine can be effective but also has a slow effect. Based on these problems, Micro-Chinese Medicine was developed by Shijiazhuang Kidney Disease Hospital, with fast medicine effect and good therapeutic effect. Generally speaking, there are three advantages of Micro-Chinese Medicine Osmotherapy in treating Polycystic Kidney Disease (PKD).

Firstly, high medicine effect: through the application of strong Ultrasonic Cavitation, Traditional Chinese Medicine turns into Micro-Chinese Medicine particles which is more than 1000 times smaller than former. By this way, effective composition of Chinese Medicine can be spilled out fully, which can improve the permeability of medicine. With medicine permeability improving, medicine particles can enter into kidney lesions directly and freely. These medicine particles can combine with remained and damaged molecular chain of kidney lesions after entering into kidney, forming new renal tissue and cells. Besides, Micro-Chinese Medicine also has the characteristics of fast operating speed, strong pertinence and professional effect, etc. Patients can have direct feelings of fast relieved symptoms and reduced painful feeling.

Secondly, Micro-Chinese Medicine can enter into kidney lesions directly. Back Shu Points are the special acupoints that Qi of Zang-Fu (internal organs) transfuses on back. When there is disease on Zang-Fu, abnormalities can be found on relevant back Shu Points. By using osmosis machine, Micro-Chinese Medicine can enter into kidney lesions directly through Back Shu Points and release highly effective composition of Chinese Medicine to repair kidney lesions. This can make cyst internal pressure higher than internal pressure of blood pressure, which is beneficial to make tiny molecular and water permeate into blood vessel, and excrete these substances out of body, reducing cyst pressure directly. Meanwhile, Micro-Chinese Medicine can also repair endothelial cells on cyst wall and prevent these cells secreting cyst fluid with the purpose of shrinking cysts.


Thirdly, Micro-Chinese Medicine can locate lesions accurately. According to characteristics of computer wave group, mid-frequency currents with different wavelengths and wave shapes are set. Under the action of osmosis machine, active substances of Micro-Chinese Medicine carried by current can get into kidney directly. The length from back kidney region to kidney is taken as the length of wavelength after computer determination. Medicine can enter into kidney lesions within 1 minute with less attrition. Besides, this can activate immune system of patients who have a lower immunity, promoting antibody production and balancing disorder condition of immune system. Micro-Chinese Medicine can prevent kidney damage caused by cystic pressure, reduce mesangial cell proliferation and slow the speed of Glomerular Sclerosis, which can recover injured renal function, improve body condition and strong disease-resistant ability, with fast and lasting effect.

Can Polycystic Kidney Disease (PKD) Relapse

Polycystic Kidney Disease (PKD) is a common among clinical Kidney Disease, and treatment is the key in the process of Polycystic Kidney Disease treating. In Western Medicine, operation is the most common treatment. Though operation can have some certain effect on treating Polycystic Kidney Disease, it can not block Renal Fibrosis which is the root cause of this disease aggravation. Under this condition, Polycystic Kidney Disease can be worsened with frequent recurrence.

In Western Medicine Treatment, removing cysts by operation is widely used to treat Polycystic Kidney Disease (PKD). For example, puncture operation and cyst decortication have been applied in clinical practice for many years. These operations can relieve clinical symptoms obviously and gain supports from many patients. But all these operation can only remove or reduce some larger cysts, which can relieve cystic pressure on healthy tissue, increase kidney blood flow and relieve clinical symptoms in a short time. They can not treat Polycystic Kidney Disease radically. Once patients catch a cold or infection, this disease relapses easily.

Based on the disadvantages of Western Medicine Treatment, Shijiazhuang Kidney Disease Hospital has developed distinctive Chinese Medicine Treatment, Micro-Chinese Medicine Osmotherapy, through many years of clinical practice and research. Micro-Chinese Medicine Osmotherapy can treat Polycystic Kidney Disease starting with blocking Renal Fibrosis, which can prevent this disease relapsing effectively.

Active substances of Micro-Chinese Medicine can act on cyst wall to improve microcirculation of cyst wall, which can increase cyst fluid reabsorption and reduce cyst fluid secretion. Through this way, cysts can be shrunk gradually and the pressure on healthy kidney can be decreased, prolonging patients’ life greatly.


As long as patients accept treatment that can block Renal Fibrosis, repair injured renal inherent cells and inhibit cysts growing effectively, disease recurrence can be avoided. Then patients can have a longer time, living as normally as other healthy person.

Diagnosis Methods of Polycystic Kidney Disease (PKD)

An early diagnosis is very important for Polycystic Kidney Disease (PKD) to accept timely treatment. If effective treatment can be taken in time, this disease can be worsened with easy recurrence, causing Renal Failure, or even Uremia. Well then, how to make sure that whether patients get Polycystic Kidney Disease or not and can exact diagnosis depend on some symptoms only? The answer is “not”.

Firstly, main clinical symptoms of Polycystic Kidney Disease: continuous or paroxysmal pain on waist and abdomen usually happens as primary symptoms, and painful feeling will be more serious after tiredness; Haematuria is a typical symptom happened among nearly half Polycystic Kidney Disease patients, expressed by intermitted gross Haematuria without pain; Abdominal masses in various sizes can be touched on upper abdomen flank, sometimes complicated by Hypertension with vertigo and headache; Renal Insufficiency can be found by obvious abnormality of renal function tests, with low but fixed urine specific gravity.

Secondly, Body Check: unilateral or bilateral kidneys can be touched in nodule shape through body check. Pressing pain can be felt when there is a infection. 50% patients have increased size of waist.

Thirdly, Assistant Tests:

(1) Routine urine test: no abnormality can be found in early stage, and microscopic Haematuria can be found in middle and late stage. Some patients may have Albuminuria. White Blood Cells and pyocyte can be found when there is complicated by Stones and Infections.

(2) Urine osmotic pressure test: even in the early stage when there is only very few cysts, expressions of renal concentrating function damage can be observed. This means that this damage may not be related with kidney structure damage only. Instead, it may also be related with renal insensitivity to antidiuretic hormone. Renal concentrating function decline happens before glomerular filtrating function decline.

(3) Serum creatinine is increasing progressively with kidney compensatory ability decline. Creatinine clearance rate is a more sensitive index.

(4) In KUB plain film, increased kidney image can be seen with irregular shape.

(5) Through IVP, deformation tendency of compressed renal pelvis and renal calices can be found. Renal pelvis and renal calices can be found in strange spiderlike shape. Renal pelvis is plain and wide, while renal calices neck become longer and thinner, showing a curved shape.

(6) Through Type-B Ultrasonic examination, a large number of shadows can be found in bilateral kidney region.

(7) Bilateral kidney enlargement can be found in CT examination, with lobulated shape. Many cysts with thin cyst wall can be found inside fluid.


If patients doubt they get Polycystic Kidney Disease, they should go to normal hospital for a whole body checks. Taking medicine by their own choice is forbidden, which can lead to some unnecessary problems.

Haematuria of Polycystic Kidney Disease (PKD) Patients

Recurrent Haematuria is a problem most patients are worried about, and how to prevent Haematuria recurrence has also gained high attention from Polycystic Kidney Disease (PKD) patients.

Haematuria is more common when patients are suffering from Hypertension and kidney enlargement, mainly caused by small blood vessel rupture near cysts. Besides, urinary tract infection and Kidney Stone can also cause Haematuria.
Haematuria can last for one or several days. At this moment, patients should take a bed rest and increase liquid intake. Some proper medicines can be taken to treat relative symptoms. If blood produced by blood vessel rupture enters into cyst directly, there will be severe pain instead of Haematuria. Repeated Haematuria is related with renal function injury, so patients should avoid active bleeding actively.

It is more difficult to treat Haematuria caused by Polycystic Kidney Disease than Haematuria caused by other Kidney Diseases. Clinical Haematuria caused by Polycystic Kidney Disease is easier to relapse. Generally, Haematuria can disappear in 4 to 8 days after medicine treatment, but it appears for another time not long after disappearing, especially for patients who suffer from Polycystic Kidney Disease. The more frequent Haematuria of PKD relapses, the higher risk and ganger of patients get end stage Kidney Diseases. Treating Haematuria caused by Polycystic Kidney Disease should start with many aspects:

Firstly, when Haematuria happens, patients should pay more attention on controlling infections. Most Polycystic Kidney Disease (PKD) patients are easy to get renal infections once Haematuria happened. These infections can worsen Haematuria.

Secondly, treatment that can activate blood, eliminate stasis and improve blood circulation should be taken to treat this disease. Growing cysts compressing renal parenchyma can cause glomerular ischemia and anoxia, which is reason why Polycystic Kidney Disease usually happens with so many complications. Therefore, methods that can dilate blood vessel, improve blood circulation on cyst wall and increase permeability of cyst wall should be taken to increase renal blood perfusion, speed up reabsorption of cyst fluid and prevent cysts keeping growing.


If only Polycystic Kidney Disease (PKD) patient can block Renal Fibrosis, repair injured renal inherent cells and inhibit cyst growing effectively, Polycystic Kidney Disease (PKD) as well as its complications, Haematuria included, can be treated. Then patients can live a normal life healthily when carrying this disease.

Can Polycystic Kidney Disease Be Treated without Operation

Polycystic Kidney Disease is a kind of genetic Kidney Disease which refers to many cysts appeared in renal cortex and renal medulla. Among treatments of Polycystic Kidney Disease, cyst puncture, cyst decortication and Nephrectomy are mainly adopted. But with social science development, disadvantages of these operations are appearing gradually. It has been proved that operations of treating Polycystic Kidney Disease can not meet patients’ needs any more.

The first disadvantage: operation can only treat surface problems instead of starting with disease cause. Surgical operation is good at removing lesions in order to eliminating discomforts caused by neoplasm, but it can not treat the disease radically. Either puncture or decortication can only treat Polycystic Kidney Disease starting with larger cysts, playing limited role in dealing with smaller cysts. Besides, with large cysts removed, internal pressure reduces at the same time, which can make small cysts grow more rapidly, damaging renal function further. For this reason, surgical operations are not suggested to treat Polycystic Kidney Disease in order to prevent vicious circle which can worsen renal function into irretrievable damage.

The second disadvantage: both Nephrectomy and Kidney Transplantation needs a really high cost with unpredictable result. Most people think Nephrectomy and Kidney Transplantation are good ways to treat Polycystic Kidney Disease radically, and they are indeed. But as a large trauma operation, Nephrectomy is a serious test for patients. In addition, due to genetic feature of Polycystic Kidney Disease, when patients remove sick kidneys, acute failure may happen to another kidney. As for Kidney Transplantation, besides expensive cost and difficulties of matching, reject action that may appear after operation can make most patients shrink back.


Due to the disadvantages of surgical operation, most patients turn their attention to Chinese Medicine. Micro-Chinese Medicine Osmotherapy can block Renal Fibrosis and relieve illness condition. The core technique of this treatment is to micronize Chinese Medicine with good effect on treating Kidney Disease in order to fully release and mix effective composition of Chinese Medicine. Then with the help of Osmosis machine, this treatment can make effective medicine enter into renal lesions directly in an external application. This new developed treatment can avoid side effect of oral medicine on one hand, and on the hand it achieves the goal of making effective medicine enter into renal lesions directly.

Complications Caused by Polycystic Kidney Disease (PKD)

In recent years, the incidence of Polycystic Kidney Disease (PKD) is on a rise. Once patients get infections, cold or external pressure, cyst internal bleeding can happen, causing sharp pain. Bleeding may be caused by complicated tumor on cyst wall. When Polycystic Kidney Disease patients accept normal treatment of Polycystic Kidney Disease, they should also prevent kinds of complications happening actively in order to avoid illness condition aggravation. Well then, what complications can Polycystic Kidney Disease cause?

Firstly, Kidney Stones and Kidney Calcification: when more serious pain, colic or gross Haematuria appear, patients may have the possibility of getting complicated Stone.

Secondly, urinary tract infections: this includes cystitis, nephropyelitis, cyst infection and perinephric abscess. As for female, instrumental examination is a dangerous factor that can cause urinary infection. If White Blood Cell Cylindruria can be found and patients have quick reaction to anti-inflammation treatment, it is beneficial to diagnose nephropyelitis. Blood Culture shows positive and local pressing pain may point to cyst infection and infectious cyst can be found through CT examination.

Thirdly, cyst cancerization: when patients have symptoms of pain on kidney region, Haematuria regulation change, increasing blood sedimentation as well as Anemia unequal to renal function or globalism, they should be aware of complicated Kidney Cancer. Timely CT examination is necessary and sometimes renoarteriography is needed.


When cysts are located in the bottom of kidney, clinging to ureter, this can worsen hydronephros, and pressure on renal pelvis from urine can cause pain on back. Besides, this can also lead to kidney infection.

Spring Diet for Polycystic Kidney Disease (PKD) Patients

Polycystic Kidney Disease (PKD) patients should have a proper diet, especially in spring with changeable temperature. Patients should choose a scientific diet according to their body condition. As for the diet of Polycystic Kidney Disease (PKD) patients, some points are listed as follows:

Firstly, polluted food which can cause gastrointestinal disease or even more serious poisoning and threat to life is forbidden. For this reason, patients should pay more attention on food cleanness. They’d better avoid taking food outside, especially food from street stalls.

Secondly, eating amount is also limited for Polycystic Kidney Disease (PKD) patients. Both too much intake and too little intake are harmful to patients’ body condition. If patients take less food, they are easily have malnutrition, while too much intake can damage digestive and absorbing function of spleen and stomach, causing obstruction of Qi and blood circulation. It patients eat too much greasy food, they can get internal heat problem easily. Therefore Polycystic Kidney Disease (PKD) patients should have many meals but little food at each in order to keep necessary energy and nutrition for body.

Thirdly, Polycystic Kidney Disease (PKD) patients should have a diet with low salt and low fat. Beef, mutton, animal viscera as well as spicy and stimulating food are forbidden. More fresh vegetable and fruit are necessary. Patients are advised to take renal function tests every 3 months regularly in order to prevent renal function being damaged.

Fourthly, Polycystic Kidney Disease (PKD) patients should avoid uncooked, cold and icy food which can damage Yang of spleen and stomach. While too much spicy and hot food can cause heat accumulation in stomach. Much more details should depend on patients’ individual condition.

Though a scientific diet is helpful to keep patients’ health, the key of treating Polycystic Kidney Disease (PKD) is still proper treatment. Micro-Chinese Medicine Osmotherapy which has a distinctive effect on treating Polycystic Kidney Disease (PKD) is suggested to patients. It has been proved by clinical practice that this treatment has a good effect on treating Polycystic Kidney Disease (PKD).


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New Treatment of Polycystic Kidney Disease (PKD)

The key of treating Polycystic Kidney Disease is to shrink cysts in order to avoid compressing on kidney by growing and increasing cysts. Once cyst fluid secretion can be controlled effectively, cysts can be reduced and this disease can be controlled completely.

When there is a local infection on cysts, patents have painful feeling. With cysts growing and increasing, they will replace healthy renal structure, causing renal function decline. Clinically, High Blood Pressure, abnormality routine urine test and renal function tests can be found. Therefore, timely treatment is necessary to be taken with the purpose of controlling illness condition.

Western Medicine usually treats Polycystic Kidney Disease (PKD) through two methods: puncture and surgical operation of removing cysts. Both the two methods can remove larger cysts effectively. But when large cysts are removed, they will leave more space for smaller cysts which can grow rapidly without pressure from large cysts. Under such circumstance, kidney is damaged for a second time. For this reason, the most disadvantages of Western Medicine is that it can only treat surface symptoms instead of treating the disease itself.

In order to solve the problems of Western Medicine, Micro-Chinese Medicine Osmotherapy is developed after many years of clinical practice to treat Polycystic Kidney Disease (PKD). This treatment has solved Traditional Chinese Medicine limitation of slow absorption and delayed effect on one hand, and on the other hand, it prevents this disease relapsing after patients healing.

After entering into kidney cysts, active substances of Chinese Medicine can play a fatal role in inhibiting proliferation of epithelial cells on cyst wall. Once epithelial cells of cyst wall stop secreting cyst fluid, cyst fluid reduces with decreasing cyst internal pressure, and then cysts shrink. Through these methods, cystic pressure on kidney can be relieved and renal function can be recovered gradually.


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What is Serum Creatinine

Serum Creatinine is mainly produced by the decomposition and metabolism of muscle creatine of human body. Therefore it is closely related with total muscles amount and seldom affected by diet; tiny amount of serum creatinine comes from digestive protein in human body, having tiny influence on serum creatinine. Serum creatinine is one of the most significant indexes of renal function injury in clinical practice.

Clinical meaning of serum creatinine:

Serum creatinine is a normal metabolic waste of human body, excreted out of human body after filtrated by glomerulus. Generally, normal value of serum creatinine for healthy adult is 44-133 umol / L (0.5~1.5 ml / L). When glomerulus filtrating function is normal, fasting serum creatinine keeps stable, which means less than 133umol / L. This indicator is usually applied in clinical practice to make a preliminary judgment of glomerulus filtration function.

Serum creatinine test is an important indicator to diagnose Renal Failure and it is seldom affected by diet, so serum creatinine can reflect glomerulus function better than blood urea nitrogen. However, normal serum creatinine does not mean ordinary glomerulus filtration function. In other words, serum creatinine can be normal in Renal Insufficiency Compensatory Stage. Serum creatinine increases until renal function losses 70%. Therefore, serum creatinine is not an accurate indicator to judge renal function damage and glomerulus filtrating rate in early stage. One point is certain that once serum creatinine increases, this disease has already developed into Renal Insufficiency. Clinically, serum creatinine value is usually used to judge the severity of renal function.

When serum creatinine is less than 186 umol / L, it is Renal Insufficiency Compensatory Stage; when 186-442 umol / L, it is Renal Insufficiency Decompensatory Period; when 442-707 umol / L, it is Renal Failure; when more than 707umol / L, it is Uremia period.


Therefore, serum creatinine testing has great clinical significance of diagnosing renal failure and observe illness condition as well as prognosis.

Renal Fibrosis of Polycystic Kidney Disease (PKD)

Due to congenital hereditary gene mutation, factors that can cause cyst growing are released, causing abnormality to basement membrane of renal tubule. Besides, growth factors, like EGF, TGF-βand IGF , which can speed up proliferation and secretion of epithelial cells on renal tubular wall are released continuously, and all these factors can cause and aggravate Renal Fibrosis.

Epithelial cells proliferation can cause renal tubular obstruction, leading to liquid retention which can swell into cyst in upper tubule. Besides, proliferation can also cause half-obstructed condition at cyst neck, which can block fluid flow out. Then cysts grow bigger and bigger.

Growing and increasing cysts compress kidney further, which can cause renal ischemia and anoxia, starting the process of Renal Fibrosis. Once Renal Fibrosis begins, it continues to produce a series of nephrotoxic cell factors and growth factors, all of which can stimulate epithelial cells of renal tubule to have Phenotype transformation, producing Myofibroblast, secreting and synthesizing Extracellular Matrix (ECM) which is difficult to be degraded.


With Renal Fibrosis developing further, more ECM is synthesized with less degradation, which leads to unbalance between ECM synthesis and ECM degradation. Large amount of ECM accumulation and deposite can cause glomerular sclerosis and renal tubular atrophy. Then fibrous tissue will replace healthy nephron more and more.

Polycystic Kidney Disease (PKD) complicated with Polycystic Liver Disease

Polycystic Kidney Disease (PKD) is always complicated by Polycystic Liver Disease which means than there are more than three cysts forming in liver, located along hepatic duct. Generally, female are a little more than male among such patients. Incidence of this disease increases from 20% at 3 years old to 75% at 70 years old, with familial inheriting tendency. Patients who survive for more than ten years after successful allograft renal transplantation suffer from Polycystic Liver Disease at the same time. Polycystic Liver Disease is mainly caused by excessive proliferation of bile duct epithelia and interstitium which can cause multi-cysts to liver fibrous tissue, including dilatation of both intrahepatic bile duct and extrahepatic bile duct, limited dilation of intrahepatic bile duct and congenital hepatic fibrosis. Besides, estrogen can also affect liver cysts growing.

As for the sizes of liver cysts, the tiny one can be found under microscope and the big one may be as large as the whole abdominal cavity. And liver volume becomes huge from normal size. Liver enlargement caused by cysts can compress healthy liver parenchyma, which causes liver atrophy. If liver parenchyma can be protected effectively, liver function can keep in a normal range.


Abdominal Type-B Ultrasonic examination and CT scan are reliable methods of diagnosing cyst internal bleeding, while MRI examination has significant role in distinguishing Hemorrhagic liver cyst or non-Hemorrhagic liver cyst and other liver diseases.

How to Treat Polycystic Kidney Disease Uremia

The sufferer has got Polycystic Kidney Disease (PKD) and Polycystic Liver Disease for more than 20 years. Her urine volume is about 800ml every day. Renal function test shows Serum Creatinine 872umol/L, and Urea Nitrogen 34.2mmol/L
After Admitted in our hospital for 26 days, the sufferer presents strong sensitivity to micro Chinese medicine. ‘In the past, the kidney area touched rather hard, but now it feels soft gradually when I touch it during these days.’ She said. The most outstanding curative effect for her is that the serum creatinine declines to 264umol/L, urea nitrogen declines to 12.3mmol/L, urine becomes turbid and odour increases and urine color becomes dark. This result surprised every body, including patients’ attending doctor who did not think the recovery so rapid.

Polycystic Kidney Disease (PKD) is the chief reason to cause Uremia, the increasingly swelling cyst can press normal nephrons, which damages the nephrons and Renal Insufficiency. There are two chief methods to cure Polycystic Kidney Disease (PKD), one is needle puncture and the other is Cyst Decortication. These approaches can remove some big cysts, but when they are removed, small cyst will grow rapidly without big cysts' pressure, and they replace the original big cysts gradually and continue to damage kidneys. Therefore, the greatest disadvantage of operation is to treat symptoms rather than to cure the disease.


As to these conditions, we adopt Micro Chinese Medicine Osmotherapy. Micro Chinese Medicine penetrates into the cysts, and it can exploit the function to improve blood circulation and eliminate stasis in body. Materials within the cysts can be decomposed into smaller molecules which access into blood flow and go out of the body through kidney excretion. Intracapsular pressure gets decreased and cysts become small. Renal function begins to recover gradually. The level of creatinine and Urea Nitrogen can low down Naturally as well.

Can Pregnancy Cause Polycystic Kidney Disease (PKD)

Most married women ask doctors the question that whether pregnancy can cause Polycystic Kidney Disease (PKD) or not. Clinically, Polycystic Kidney Disease (PKD) is a kind of genetic disease. It can be divided into two types: Autosomal Dominant Polycystic Kidney Disease (ADPKD) and Autosomal Recessive Polycystic Kidney Disease (ACPKD), and the former is more common. ADPKD is a kind of autosomal dominant inheritance, having the characteristics of familial aggression and equal incidence to both male and female. Many factors can cause Polycystic Kidney Disease (PKD). For this reason, patients should pay more attention on their daily life in order to prevent this disease happening.

Generally, influence on Polycystic Kidney Disease (PKD) patients caused by pregnancy mainly depends on the condition of renal function. Tough there is no exact evidence than can prove that pregnancy can accelerate illness condition development, worse prognosis can be found among patients who are pregnant for several times with complicated High Blood Pressure. About one fourth PKD patients can get High Blood Pressure or their origin High Blood Pressure can be aggravated during the process of pregnancy. Therefore, multiple pregnancy can play a vicious role in prognosis of PKD patients, and this condition only refers to patients who still have normal renal function. While pregnant patients whose renal function is not normal get much more ganger from pregnancy.

Polycystic Kidney Disease Can Arouse Nephrotic Hypertension

The occurrence of Nephrotic Hypertension caused by Polycystic Kidney Disease (PKD) is resulting from that cysts press normal kidney tissue and ischemia, anoxia and low blood perfusion occur in kidney. Progressive pathological lesion of kidney will happen if PKD patients with Hypertension can not control the disease in time. Renal fibrosis becomes more severe and serum creatinine increases. Aggravating Kidney Disease will further hike blood pressure continuously, which can enlarge heart and cause heart failure. Some patients’ conditions get worse rapidly. Renal Insufficiency may happen if renal tissues are pressed and renal functions are damaged, which will develop into Uremia finally.
Treatment of Nephrotic Hypertension caused by Polycystic Kidney Disease (PKD)
There are some differences between Primary Hypertension and Nephrotic Hypertension caused by Polycystic Kidney Disease (PKD). For the latter, the crux of treatment is to treat Polycystic Kidney Disease (PKD). The priority is to reduce cysts’pressure to kidney and renal parenchyma, postpone or block the progression of Renal Fibrosis. Only by this, can Hypertension be treated radically. The aim of Micro Chinese Medicines is to decrease cysts and reduce the damage of renal tissue fundamentally.

Dilating blood vessels, general blood circulation can be improved so as to attain treatment.

By expanding renal arteries, blood perfusion increases, so do general microcirculations, oxygen supply and metabolism gets improved, which can change the activity of cyst wall cell, increase permeability and bring away cyst liquid. Meanwhile the secretion of cyst wall cell can be blocked by expanding renal arteries, so as to make cysts shrink.


With the active ingredient in Chinese medicine playing efficacy, the pressure of cysts to nephrons around can be relieved; ischemia and anoxia of normal kidney tissue can be moderated so as to delay the progression of renal fibrosis. This not only reduces the occurrence of Hypertension, but makes vasodilatation factor increase with the decrease of angiotensin. Besides blood circulation on cyst wall can be improved and blood vessels become flexible as well. What’s more, the active ingredients can target the damaged fibrosis tissues, Myofibroblast and immune complex. After the active ingredient reaches the targets, a range of effective components can be released which can degrade fibrous tissue and immune complex in the lesion. In addition, the active ingredient can supply requisite material to repair the damaged nephrons. Only renal structure gets repaired, can renal functions be rebuilt and recovered and clinical symptoms get relieved.

Why Polycystic Kidney Disease (PKD) Patients Get Hypertension

In Polycystic Kidney Disease (PKD), countless cysts with different sizes spread over renal cortex and medulla. Cysts occupy much more space than renal parenchyma. Kidney is in grapelike shape with obvious enlargement.

With illness condition developing, most PKD patients get Hypertension and male patients are more obvious than female patients. The level of blood pressure is highly related with kidney size, cyst number and cyst size. The main reason of Hypertension is cysts compressing. Growing and increasing cysts compress some renal blood vessels, which can reduce local blood flow. When renal receptor get this information, it will reflexly give an order of secreting more rennin, and then angiotensin concentration increases, which make blood vessel shrink, increasing blood pressure. Hypertension and renal injury can aggravate each other. Generally, once PKD patients get Hypertension, it means that their renal function is about to be injured or has already been injured. Therefore, PKD patients should pay high attention on controlling blood pressure.

Once Polycystic Kidney Disease (PKD) patients have symptoms of Nephrotic Hypertension, they should accept treatment actively instead of self-medication. If PKD patients take some nephrotoxic medicine to reduce blood pressure unconsciously, their illness condition can aggravate rapidly, or even death can be caused. So patients should take medicine under doctors’ advice.

Nephrotic Hypertension caused by Polycystic Kidney Disease (PKD) is different from primary Hypertension. As for Hypertension caused by Polycystic Kidney Disease, the key of treating Hypertension is to treat Polycystic Kidney Disease through methods of reducing cystic pressure on kidney and renal parenchyma as well as delaying or blocking Renal Fibrosis. Only by this way, Hypertension can be treated radically.


Micro-Chinese Medicine Osmotherapy can treat Polycystic Kidney Disease (PKD) starting with shrinking cysts, which can prevent renal tissue being damaged from its root cause. With active substances of Chinese Medicine playing their role, they can reduce cystic pressure on surrounding renal tissue, relieve renal ischemia and anoxia as well as delay the process of Renal Fibrosis. Though these methods, the occurrence of Hypertension can be delayed. Besides, Micro-Chinese Medicine can also degrade Extracellular Matrix and immune complex, provide necessary substances to kidney and repair kidney structure. Once injured kidney is recovered, Polycystic Kidney Disease can be relieved and Hypertension caused by Polycystic Kidney Disease can also be relieved.

What Is The Harm of Polycystic Kidney Disease

Polycystic Kidney Disease (PKD) means that many cysts occur in cortex and medulla of the kidney, which is a kind of hereditary kidney disease. According to the hereditary patterns, it can be divided into two types. The first one is autosomal dominant inheritance, also known as adult Polycystic Kidney Disease. The second one is autosomal recessive inheritance, also known as infantile Polycystic Kidney Disease. The adult Polycystic Kidney Disease is common in the clinical practice, which accounts for 5%-10% in the total amount of End Stage Renal Failure.

With age growing, cysts develop gradually. Manifestations in early stage include pain in waist, blood pressure increase, and abnormal kidney structure which is presented in Type-B Ultrasound Examination. Cysts will continue growing, pressing and damaging nephrons around if they are not controlled effectively in this stage, which can start the progression of Renal Fibrosis. In Urine Routine Test, protein and hemocyte can be figured out. If the progression of Renal Failure can not be blocked efficiently, PKD patients present serum creatinine increase and glomerulus filtration rate decline, and develop into End Stage Renal Failure.


In the treatment of Polycystic Kidney Disease (PKD), the top priority is to shrink cysts and block the progression of Renal Fibrosis. The series of medicines of Micro-Chinese Medicine Osmotherapy can dilate blood vessels around cysts, restrain the activity of epithelial cell on cysts wall, and shrink cysts. Therefore, renal parenchyma no longer gets pressed and initial factors of Renal Fibrosis can be decreased and renal functions cn be protected. The active ingredients of Micro-Chinese Medicine Osmotherapy have the function of anti-inflammation and anti-coagulation, which can reduce nephrons’ further damage so as to block the progression of renal fibrosis; the active ingredient in the medicine can provide requisite nutrient for damaged nephrons recovery. This therapy builds a solid foundation to treat Polycystic Kidney Disease (PKD) and renal function damage rapidly, and it has attained pleasant curative effect in the clinical practice.

Case Analysis of PKD Renal Insufficiency

Patient: Li Guizhen, female, Guilin Guangxi Province

Main cause: patient had got right-side waist swelling without obvious inducement. No other symptoms are found. Through Type-B Ultrasonic examination in local hospital, the largest cyst is 6.6cm. Patient was diagnosed as Polycystic Kidney Disease in local hospital which offered no treatment to patient. Her two brothers and two sisters also have this disease. No medicine allergy history.

Test in our hospital: patient’s body check result is normal, showing simply genetic Polycystic Kidney Disease. Through Type-B Ultrasonic examination, bilateral kidneys size enlarges with smooth capsule. Many echo free areas with various sizes can be found inside. Largest cyst of left kidney, 3.7cm x3.3cm; largest cyst of right kidney, 6.1cm x5.4cm. Different sized echo free areas can be also found in liver region. Through renal function test: creatinine, 245umol/L.

Diagnosis: Polycystic Kidney Disease, Polycystic Liver Disease, the third stage of Chronic Kidney Disease, Renal Insufficiency Stage.

Treatment process: after patient being hospitalized, Micro-Chinese Medicine Osmotherapy was adopted.

Jun 6th, 2008, patient felt less painful on her waist. After 9-day treatment, patient felt much better than before. And she continued to ask questions about her disease and she was confused that why so many family members get this disease.

Jun 30th, 2008, waist discomfort was relieved further. Patient felt less pressure in heart and she began to have a better sleep. Doctors told her to accept treatment continuously and observe the development of illness condition closely.


Jul 10th, 2008, waist discomfort disappeared completely. Patient had a very good looking. Through communication, patient said that she had an improved appetite and discomfort on waist disappeared completely. Symptom of cold intolerance was also relived and sometimes sweat appeared in her hands.

Tongue Diagnosis in Looking Diagnosis of Chinese Medicine

Tongue diagnosis is the most characteristic diagnosing method in looking diagnosis of Chinese Medicine. Tongue diagnosis includes looking tongue body and tongue coating which means the coated fur on the surface of tongue body. Tongue body can show the condition of healthy body energy while tongue coating can show the severity of evil factors in human body. If external evil factors enter human body and affect digestive function of stomach and spleen, tongue coating will become thick. If tongue surface is smooth, just like a mirror, it usually means too much weak healthy body energy.

The reason why tongue coating can reflect disease is that tongue has a close relationship with internal organs through stomach Qi connection. Stomach Qi refers to the functional condition of stomach and spleen. Its physical and pathological condition has very important influence on other internal organs.


Tongue observation in Chinese Medicine includes observing color of tongue body, color and thickness of tongue coating as well as tongue shape and other factors. In clinical practice, tongue condition can reflect the physical and pathological condition of organic body more correctly, so people usually consider tongue as a mirror of body physical and pathological condition.