Kidney Failure Caused by Polycystic Kidney Disease

According to the clinical statistics, more than half patients with Polycystic Kidney Disease can developed into kidney failure if it can’t be controlled well. As we know, the cysts will enlarge with the increase of age. Being different from other types of kidney diseases, the pathology injury of the kidney is caused by the mechanical pressure. This is because: with the enlargement of the cysts, they will compress the surrounding glomerulus intrinsic cells and gradually damage the nephrons, which will gradually cause the lost of the renal function and lead to the renal fibrosis. Then kidney failure will appear.

The process of Polycystic Kidney Disease causing kidney failure is a long procedure. In addition, the early symptoms of kidney failure are not very obvious, so many patients didn’t realize that they have suffered from this disease until more than half the nephrons have been damaged. But at this time the illness condition is relatively serious. Due to strong compensatory ability of kidney, there are few obvious symptoms in the early stage of this disease, and related symptoms will not occur until more than 90% to 95% kidney function is lost. However, at this moment, the illness condition of patients has already developed into end stage. In this stage, patients may have symptoms of oliguria, anuria, nausea and vomiting as well as urea smell in mouth, etc. Sometimes, patients with more serious condition may even have symptoms of coma, hyperspasmia and so on. Here are some common symptoms appeared in early stage of kidney failure caused by PKD.

Firstly, tongue is pale and teeth-print can be found at tongue edge. Besides, enlarged tongue as well as edema and fester at tongue root, all of which are considered as phenomenon of Kidney failure in Chinese Medicine.
Secondly, patients feel tireless and exhausted without any reasons. In Chinese Medicine, light tiredness is due to spleen while serious tiredness is related with kidney.

Thirdly, patients do not sweat for long term and they usually scare of cold. Besides, increasing night urine or frequent urination, oliguria and urine difficulty are all early symptoms of kidney function injury.

Fourthly, some other symptoms like low appetite, asitia, nausea, vomiting as well as gastrectasia also appear in early stage of Renal Failure and Uremia. Many patients have lost the best treatment timing because they always mistake their disease as stomach illness.


Once PKD patients are found early symptoms of kidney failure, they should go to hospital for proper treatment as early as possible in order to delay the development of this disease.