2016年9月30日星期五

Can Polycystic Kidney Disease Take Exercise

Can Polycystic Kidney Disease take exercise? This is a puzzling problem for PKD patients. According to this problem, specialists on Kidney Disease notice that PKD patients can take physical exercise properly and scientifically, but excessive exercise is forbidden. As for PKD patients, which standard of daily exercise and work can not affect their body health? Normally, this depends on patients’ individual illness condition. Generally speaking, there are very few problems before patients are 30 years old. Though cysts of most PKD patients begin to compress each other, the pressure caused by cysts is tiny in this period. So patients can take some safe exercise at this moment, but crashing exercise like basketball should be avoided. Usual light exercise can not affect kidneys normally.

If patients are about 40 years old, they should pay more attention on daily work and life. Because cysts produce larger pressure in this period and strenuous exercise usually bring cyst rupture to patients. For this reason, patients should avoid pressure or collision on kidney region. Especially for a housewife, they should be more cautious when she is looking after a baby in order to prevent baby kicking her kidney region.

As for patients who had suffered from Haematuria before, they are required to pay more attention on their daily activity, because cysts of these patients are much easier to get cyst rupture. In order to prevent Haematuria recurrence, patients should take some exercise with less bending angle and lighter strength burn. Besides, these patients should take chairs with similar height of their knee when they are sitting. Walking and slow run can be taken as main morning exercise.


In a word, PKD patients who want to take some exercise should take a proper exercise volume and avoid excessive activity. Besides, the most important thing is to treat PKD in time and control cysts growing. Only in this way, PKD patients can have a normal life as other healthy person.

2016年9月29日星期四

Immunotherapy to Treat Polycystic Kidney Disease

With deep research on PKD treatment, scientists has made a new break—Immunotherapy. Before learning more about Immunotherapy of treating PKD, the first thing should be done is to know what is Polycystic Kidney Disease and how does it occur.

Immunotherapy treats PKD starting with recovering and renewing injured renal cells. When cysts are still small, they seldom cause damage to renal parenchyma. But with cysts growing, they will compress surrounding renal tissue and renal blood vessel, which can lead to renal local microcirculation obstruction, causing renal ischemia and anoxia. These can damage endothelial cells of renal capillary and attract inflammatory cells infiltration in blood circulation, which speed up renal function injury and start the process of Renal Fibrous. Besides, mechanocyte distributing in renal interstitium can turn into myofibroblast which can secrete and synthesize Extracellular Matrix (ECM) and immune complex. These ECM and immune complex are not easy to de degraded. For this reason, there is an unbalance between ECM degradation and ECM synthesis. Massive ECM deposit in kidney, which causes glomerular sclerosis and renal tubular atrophy. Therefore, renal fibrous tissue will replace healthy nephron gradually. With renal function decline more and more, renal function disappear completely, which means that PKD has developed into end stage. At this moment, patients get Renal Failure or Uremia.

Immunotherapy is a kind of cell with characteristics of multi-directional differentiation and self-replication. Immunotherapy can distinguish injured renal inherent cells and recover these injured cells after they entering into kidney lesion. Besides, Immunotherapy can also produce various types of inherent cells, which can relieve the condition of renal ischemia and anoxia and promote blood circulation of cyst surface. All these methods are helpful to recycle cyst fluid. Besides, Immunotherapy can also inhibit cystic cells growing, which can shrink cysts gradually. Once renal inherent cells are repaired, they can play their function on degrading immune complex and ECM, achieving a balance between ECM synthesis and ECM degradation. Therefore, renal function recovers gradually.


Though Polycystic Kidney Disease is a kind of hereditary disease, it is not so terrible. Patients should cooperate with doctors actively. Beside, patients should pay more attention on daily diet and exercise. Regular examination is required in order to find this disease and take effective treatment as early as possible.

2016年9月28日星期三

Mental Care of Polycystic Kidney Disease Patients

Polycystic Kidney Disease should pay more attention on mental care. But why? Actually, one person’s mental condition has great influence on occurrence, development and treatment of Kidney Disease. Different mental characteristics can lead to functional disorder of internal organ and worsen Kidney Disease directly or indirectly.

In Chinese Medicine Therapy, mental factor is one of pathogenetic factors. Human body is a closely integrated organic whole. One person’s mentality is closely related with internal organic function. During the process of Kidney Disease development, mentality is also very important. A good mental mood is beneficial to make Qi flow smoothly, which is helpful to keep each internal organ operating normally. Then water metabolism as well as secretion and excretion function can be normal. All these are favorable for Kidney Disease patients to recover.
Contrarily, bad mental mood can cause Qi dysfunction and blood circulation disorder,, resulting in functional disorder of internal organs which can cause or worsen illness condition.


Clinically, most PKD patients will lose confidence of overcoming the disease due to much long disease course or worsening illness condition. They may feel despondent and pessimistic, or even despairing. For this reason, other family members or patients friends should console patients frequently and encourage patients to fight against with disease. Through this way, patients can cooperate with doctors actively in a favorable mood. During the process of treating this disease, patients should avoid bad mental stimulation, which is helpful for patients’ recovery.

2016年9月24日星期六

Case Analysis of Polycystic Kidney Disease and Polycystic Liver Disease

Patient Name: Zhang Chunzhi

Gender: female

Age: 62 years old

Province: Handan, Hebei Province

Diagnosis: Polycystic Kidney Disease, Polycystic Liver Disease

Main cause: patient has suffered from Polycystic Kidney Disease and Polycystic Liver Disease for more than 20 years. Bilateral kidneys are both larger than 20cm. Patient herself can touch enlarged kidney. Urine amount: 800ml with light color. Serum creatinine: 872 umol/L. BUN: 34.2mmol/L.

Treatment: after 26-day treatment in Shijiazhuang Kidney Disease Hospital, patient showed great sensitivity on micronized Chinese Medicine. She said that kidneys she has touched are not as hard and large as before.

Test result: serum creatinine, 264umol/L; BUN: 12.3mmol/L. This result is really a great surprise for patient herself and her attending doctor.


Expert comments: PKD is one of common causes of Uremia. Continuously growing cysts can compress healthy nephron, causing nephron injury. Then Renal Insufficiency occurs. According to the above, Shijiazhuang Kidney Disease Hospital adopts Micro-Chinese Medicine to treat Polycystic Kidney Disease. Micro-Chinese Medicine can permeate into cysts directly, and fully play the role of activating blood and dredging channels, eliminating blood stasis and removing obstructions in blood vessel. All these are beneficial for kidney to excrete cyst fluid. Therefore, cyst internal pressure can be reduced and cyst size can be smaller with gradually recovered renal function. As a result, creatinine and urea nitrogen decrease.

2016年9月21日星期三

Normal Treatment of Adult Polycystic Kidney Disease

Adult Polycystic Kidney Disease is a kind of congenital hereditary Kidney Disease, belonging to autosomal dominant inheritance disease, which means that this disease can inherit from generation to generation, but never skip generation. Each parent suffer from Polycystic Kidney Disease, each of their children can have 50% possibility of getting this disease. According to statistics, one in 400 to 1000 persons can suffer from Polycystic Kidney Disease.
With PKD occurring, clinical complications, cyst rupture, bleeding, inflammation and stones, appear. All these complications are expressed on patients’ body, which can decrease patients’ immunity and cause infection easily.

Generally, cyst decortication and puncture sclerotherapy are used to treat Polycystic Kidney Disease. These two operations can relieve symptoms of abdominal distension and waist pain in a short time, but other complications of Haematuria, anemia, High Blood Pressure and high creatinine can not be solved completely.
Such operations can only treat symptoms instead of treating the disease itself, which can aggravate kidney condition and cause renal ischemia and anoxia as well as glomerular low perfusion. Then patients’ renal function declines gradually and renal ability of excreting toxin decreases greatly, expressed by continuously high serum creatinine. Finally PKD develops into Uremia.

The correct way of treating Polycystic Kidney Disease is to start with recovering patients’ injured renal function and treating complications at the same time. Only in this way, PKD can be treated effectively.


As last, one point should be noted that patients should avoid any exercise that may increase cyst internal pressure; no matter they are accepting treatment in hospital or receiving consolidation treatment at home.

2016年9月19日星期一

Chronic Waist Pain of Polycystic Kidney Disease Patients

Chronic waist pain which is a common symptom of Kidney Disease should not be neglected by patients. Especially for patients suffering from Polycystic Kidney Disease, they should pay much more attention on waist pain than others, because the painful feeling may be caused by urinary tract infection or Kidney Stone caused by growing cysts, or even renal cell carcinoma can be one of the causes. Patients who suffer from light pain may feel abdominal swelling and discomfort, while patients with serious condition may feel seriously painful. Such pain can be worsened after strenuous exercise. Waist pain may be caused by pressure on renal parenchyma or renal hilus resulting from growing and increasing cysts. Sharp pain always refers to complications of Kidney Stone, hematomas or obstruction caused by renal bleeding, infections and malignant tumor, etc.

Different Polycystic Kidney Disease patients have pain of different degrees, and mental factors can aggravate waist pain of 40% patients. As for patients who suffer from waist pain mainly caused by mental factors, they should accept a systemic treatment, including mental relaxing training and distracting attention, etc. Presently, psychotherapy has been more researched, because it can avoid some danger from taking medicine.

2016年9月16日星期五

Polycystic Kidney Disease Complicated with Stone

Patient: Wu Changwei, Male, 60 years old

Diagnosis: Polycystic Kidney Disease complicated with Multiple Stone, Chronic Renal Insufficiency Compensatory Stage

Hospitalization: 22ed Jan, 2007 to 6th Feb, 2007

Main Cause: patient has suffered from intermittent waist pain for 15 years.
Test when patient went to hospital: 1. Polycystic Liver Disease; 2. Polycystic Kidney Disease; Type-B Ultrasonic result: left kidney, 22.9*9.6cm; right kidney, 17.1*9.0cm’ large cyst in left kidney, 7.8*5.8cm; large cyst in right kidney, 5.4*4.6cm; small stone can be found in cysts.

Renal Function Test: serum creatinine, 135.7umol/L; endogenous creatinine clearance, 51.5ml/min

Morse Test: renal tubular concentrating and dilution functions are damaged. Patient has symptoms of waist pain and Haematuria.

Treatment: Micro-Chinese Medicine is taken to anticoagulation, antioxidant, anti-inflammation and active blood circulation in order to protect renal function. After 10-day treatment, patient’s appetite increases and waist pain reduced gradually. Brick red granular deposite is found in urine.


Expert Comment: with cysts growing and increasing, these cysts will compress healthy normal renal tissue, causing renal ischemia and anoxia. Then renal function and renal ability of excreting toxin decline. Micro-Chinese Medicine can improve renal blood circulation and shrink cysts through methods of activating blood and dredging channels, eliminating stasis and removing obstructions in blood vessel, repairing and renewing. Through these methods, renal function can be improved, so does renal ability of excreting toxin. Besides, with cyst internal pressure reducing, the pressure on gastrointestinal tract decreases, which is helpful to improve digestive function, then abdominal discomfort can be relieved.

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