FSGS: Is It an Immunological Disease

More than 95% of kidney diseases are immunological disease and FSGS is not an exception. In order to give suitable treatment, the diagnosis like this judgment is very important. So for patients with FSGS, treatment should focus on immune regulation in order to achieve a good effect.

Overview of FSGS

It is short for focal segmental glomerulosclerosis that means some sections of kidney filters are scarred. After reading this explanation, you can know the general situation about this disease. How does FSGS associate with immunological disease?

Due to unhealthy diet or life style, their immune system is out of order and patients’ immunity is lower than before. In this physical condition, people are very easy to suffer diseases, such as infections or a cold. If their innate immune system is good, immune complexes formed during infections will be removed by immune cells. However, in patients with FSGS, the immune complexes have to stay in body and would arouse renal failure once they deposit in kidney tissues.

Inflammatory mediators will accumulate around immune complexes in kidney tissues in order to remove them. However, this inflammation will hurt kidney tissues meanwhile. When kidney cells are damaged, the filtering ability cannot be done normally. Many valuable substances in the blood will be leaked from the blood. Furthermore, over time the kidney filters would be scarring and cause loss of kidney function. Once they lose about 50%, FSGS is coming.

Immunotherapy is the correct treatment for immunological disease—FSGS. It mainly contains Immunodepression, immune regulation and immune protection.


Immunodepression will give patients some immunosuppressive agents to restrain renal inflammation in order to protect kidney cells. Furthermore, these agents are regularly needed to keep a good situation in kidneys. However, kidney cannot tolerate immune complexes for a long time. Immune regulation is essential to turn immune system to normal so as to block renal inflammation from the root. If the kidney has a serious hurt, immune protection is provided. It adopts Immunotherapy which does not only provide new kidney cells but also rebuild a new immune system to keep healthy for a long time.

Facts about Focal Segmental Glomerulosclerosis

"Save kidneys, save lives" indicates that kidney disease is a risk to threaten their lives. Focal Segmental Glomerulosclerosis (FSGS) is a kind of serious kidney disease. About 14% of patients with renal failure have FSGS and it is also the second leading cause of children renal failure. So patients need to pay more care to the kidneys in order to avoid a further damage caused by this disease.

What is FSGS? It is short for focal segmental glomerulosclerosis that means some sections of kidney filters are scarred. Usually the scarring filters take part less than 50% and the filters are the glomeruli which are used for filtering blood and removing toxic substances and excessive water from the body.

How does FSGS strike kidneys? This disease is idiopathic and many people cannot say the causes of FSGS. In fact, it is caused by a disordered immune system. Due to unhealthy diet or life style, immunity is easy to lower down. Infections would occur in this bad physical situation. During this immunoreaction, a large number of immune complexes are formed and deposit in kidneys, causing a furious inflammation to damage kidney tissues.

How is FSGS diagnosed? It is usually diagnosed with renal biopsy. Through observing several glomeruli taken from patients’ kidney tissues, doctors can indicate whether it is FSGS.

What are the symptoms of FSGS? They do not only have symptoms caused by kidney disease but also have some complications. For example:

Protein in urine

Low blood protein

High blood pressure

Swelling in parts or the whole body

Heart disease

What is treatment for FSGS?

Some therapies for symptoms

Low-salt diet that can remit swelling

Drugs for reducing high blood pressure

Anticoagulants to prevent blood clots

Statins to lower the cholesterol level

Treatment for repairing kidneys--Immunotherapy

Immunodepression medications are needed to put down the furious renal inflammation.

Immune regulation adopts Chinese herbs therapy to balance immune system to block renal inflammation from the root.


Immune protection use Immunotherapy to rebuild a new immune system to keep a good physical condition. Furthermore, it provides more new cell to form healthy tissues to improve kidney function.

Prolong Your Life Expectancy with FSGS

FSGS refers to focal segmental glomerulosclerosis that means some sections of kidney filters are scarred. Once they are diagnosed with FSGS, it would mean a bad physical condition later unless they receive effective treatment. So most people are worried about the life expectancy with FSGS.

Give more care to FSGS

In the early stage, kidney disease hardly presents a symptom to patients. So many people live with it for a long time without known its existence. When their illness condition worsens, they begin to realize the problems of kidney disease. However, if they cannot hold the best time of treatment in the early stage, their illness is hardly reversed. So in the daily life, people need to pay more care to FSGS.

Some examinations for kidney disease help to find problems early and people’s life expectancy can be prolonged by timely treatment. These examinations include:
Tests for kidney function. Blood tests can provide the number of creatinine, uric acid, BUN, Cyc C, RBP, HCY, IL-6, PTH in order to get the accurate kidney function in the early stage.

Urine examinations. For example, you can try tests of U-malb, U-TRF, U-IGG, U-GGT, U-NAG etc or the urinary protein electrophoresis to detect whether there is damage in kidney tissues.

Save your kidneys from FSGS, save your life

In order to prolong life expectancy, people need to seek the effective treatment for FSGS. When your condition has been worsened, what treatment can give you a good answer?

In this situation, you can try Immunotherapy which is a comprehensive treatment for patients and is very considerate to improve many aspects of patients. This therapy contains several methods and focus on immune regulation to achieve a good effect.


From many patients’ experience, they only have received Immunodepression in order to block the renal inflammation. At the end, FSGS relapses repetitively. So immunotherapy adds immune regulation and immune protection to help remove renal inflammation and save kidneys from the root. These two therapies adopt Micro-Chinese Medicine Osmotherapy and Immunotherapy respectively to achieve the same aim which is to keep the immune system well and eliminate renal inflammation.

Treatment of Membranous Lupus Nephritis

Membranous Lupus Nephritis flares up and hurt patients’ kidneys greatly. If not taking an effective treatment, many people would lose their lives due to seriously damaged kidneys. So choosing a good treatment is very important for patients with membranous lupus nephritis.

In order to give a good direction, a successful treatment of membranous lupus nephritis will be listed in the following:

Blood purification. When lupus starts, disordered immune system will send out many antibodies to attack healthy body cells. So they will have many complications, such as chest pain when taking a deep breath, fatigue, fever, hair loss, mouth sores, skin rash, brain and nervous system, heart disease, kidney disease and so on. Through blood purification, all of these complications can be greatly remitted.

Immunodepression. Many people with lupus nephritis are taking immunosuppressive agents to block the renal inflammation in order to reduce kidney damage. Protein in urine or other indexes will turn to normal after this step. However, most people have side effects or their other parts of body may be hurt by these drugs.
Immune tolerance. It is an strange therapy for patients. In fact, it is very simple and mainly makes full use of Immunodepression scientifically to keep the inflammation silent so as to protect kidneys.

Immune regulation. Most therapies may stop in the step of Immunodepression. And they think restraint of inflammation is enough for kidney protection. However, the disordered immune system will strike kidney again, so long-term usage of immunosuppressive agent bring about many side effects to them.

Thereby we work out and develop a therapy of immune regulation. Micro-Chinese Medicine Osmotherapy and oral Chinese decoction are mainly used to tone functions of organs and tissues. Once their immune system is kept well, lupus nephritis would not flare up.


Immune protection. It is a further therapy to improve immune system. In this step, Immunotherapy is used and new healthy immune cells can be produced to rebuild a wonderful immune system. Besides, if their kidneys lose much function, they also can provide kidney cells to kidneys and improve patients’ GFR. In this way, their lupus nephritis can be treated from the root.

Treatment for Chronic Kidney Failure Caused by Diabetes

Diabetes would lead to many complications among which chronic kidney failure is a common and dangerous one for patients. Many people with diabetes have to suffer a lot during taking dialysis and kidney transplant. However, dialysis cannot treat chronic kidney failure from the root. And graft kidney would be hurt again after kidney transplant due to diabetes. So doctors and patients all want to seek a new treatment for chronic kidney failure caused by diabetes.

Along with presence of more and more advanced technologies, patients have the hope to cast off dialysis and lead a full life. The successful treatments for chronic kidney failure caused by diabetes include:

Micro-Chinese Medicine Osmotherapy. This therapy mainly makes use of Chinese herbs to regulate the body in order to achieve a good internal environment. It is known that many complications would occur as the chronic kidney failure leads to many toxic substances deposited in the blood.

Chinese herbs can degrade toxins, dilate blood vessels and accelerate the circulation in order to clean the blood and provide relative healthy blood to every tissues and organs. So many people’s symptoms are greatly remitted after Micro-Chinese Medicine Osmotherapy.

Immunotherapy. It is the major therapy to treat diabetes and chronic kidney failure meanwhile. For these patients, these cells can produce cells of pancreas and kidneys under the inducement.


Immunotherapy need no surgery but only injection. With the homing ability, they can find the lesions in pancreas and kidney. In this way, patients will have no insulin injection to control blood sugar well and the chronic kidney failure can be treated from the root. Furthermore, kidney function will be improved greatly, so kidneys can support body to discharge toxic substances from the body. As a result, patients can lead a full life after these treatments.

The Life-threatening Complication of Diabetes – Diabetes Renal Failure

What does type 1 diabetes cause? As we all know, type 1 diabetes has negative effects on the body. The complications caused by type 1 diabetes are dangerous. Diabetes renal failure is the main cause of death in type 1 diabetes, meaning that diabetes renal failure threatens the life of diabetics.

Since there are no obvious symptoms in the early stage diabetic nephropathy, type 1 diabetics do not notice the kidney problem until some symptoms occur such as protein in the urine, swelling around the eye and eye disease. As along as diabetes kidney disease happens to them, it will quickly worsen into chronic renal failure. Subsequently, high blood pressure and general swelling will come soon. Eventually, it can lead to end-stage renal failure.

In end-stage renal failure, renal replacement therapy is required to replace the kidneys to work because malfunctioned kidneys are less able to filter the wastes and excessive fluid out of the body. Dialysis can temporarily to remove the wastes and fluid out of the blood to keep people alive. Patients need to do dialysis 2-3 times one week. Kidney transplant is a better way to solve the kidney problems. However, the insufficiency of kidney donor is the biggest barrier in front of the patients with diabetes renal failure.

Diabetes kidney disease is more common in elderly people with diabetes as long as 10 years. Thus, diabetes patients need to be wary of diabetes kidney disease. People who have diabetes for 6-10 years and persistent proteinuria are at high risk for diabetes kidney disease.

Kidney doctor advises that treat type 1 diabetes as soon as possible in case of diabetes kidney disease onset. Type 1 diabetes is horrible largely due to the type 1 diabetes renal failure.

What are the Causes of kidney failure

Kidney failure can occur from an acute situation or chronic problems.

In acute kidney failure, kidney function is lost over a period of hours, days, or in some cases, weeks. The causes of acute kidney failure are categorized based on where the injury is set.

Renal Causes

Renal causes of kidney failure (factors that damage kidney itself) mainly include:

Sepsis: the body's immune system is overwhelmed from infection and causes inflammation and shutdown of the kidneys. This usually doesn't occur with urinary tract infections.

Nephrotoxic medicines: certain medicines are toxic to the kidneys, including nonsteroidal anti-inflammatory analgesic medicines like idomethacin, ibuprofen, aspirin, etc. Other potentially toxic medicines also include antibiotics such as gentamicin, Nafcillin, and anesthetic medicines like diethyl ether.

Pre-renal causes

Pre-renal kidney failure occurs due to decreased blood supply to the kidneys. Pre-renal causes mainly include the follows:

Low blood volume due to blood loss

Dehydration from loss body fluid, examples of which include: vomiting, diarrhea, severe sweating, high fever, etc.

Insufficient fluid intake

Such medicines as diuretics may result in severe water loss

Abnormal blood flow to and from the kidney due to obstructions in renal arteries or veins

Post-renal causes of kidney failure are factors that affect outflow of urine. Common causes mainly include urinary tract stones, bilateral pelvic effusion, prostatic hyperplasia, tumors in the abdomen that surround and obstruct the ureters.

Chronic renal failure (CRF), or chronic kidney disease (CKD), is a slow and progressive decline of kidney function. The most common causes of chronic kidney failure are Diabetes and high blood pressure.

Multiple myeloma

Acute glomerulonephritis or inflammation of glomeruli, the filtering system of the kidneys. Diseases that could cause the inflammation mainly include Systemic Lupus Erythematosus, Goodpasture Syndrome, Wengener's granlomatosis, etc.

One of the complications resulting from diabetes or high blood pressure is the damage to the small blood vessels in the body. The blood vessels in the kidneys also become damaged, resulting in CKD.