What Does High Level Creatinine Mean?

Creatinine is usually considered as endogenic creatinine, which is metabolin of muscle. In muscles, creatine is mainly metabolized gradually into creatinine by irreversible non-enzyme dehydration and then creatinine will be released into blood, which is expelled from body with urine. Thus creatinine is closely related with total muscles and it is not easily affected by diet. Creatinine is micro-molecule substance, which is filtered by glomerulus and rarely absorbed by kidney tubules. Creatinine generated in body is almost completely discharged from body with urine, which is usually unrelated with urine volume. Creatinine test is a common measure in clinic used to know renal function.

High level creatinine often means kidney damage. High level of creatinie can comparatively exactly display the damage condition of renal parenchyma but creatinine is not a sensitive index. Generally speaking, because the total muscles in body is comparative stable, creatinine generation is also constant. Whether the levels of Creatinine in blood is high or low, it mainly depends on how much the kidneys expel it. As the kidneys have a great compensation function, so long as one of them maintains a normal function, creatinine will maintain a normal level.Only when GFR declines to one third of normal, will creatinine increase obviously. That is to say human kidney has a great capacity of compensation and when more than half of the renal function has been damaged, creatinine will increase. Therefore creatinine can not reflect renal decline at its early or moderate stage. When the damage of kidney is slight, people usually have no obvious uncomfortable feelings. Consequently, when many people really represent the symptoms such as nausea, vomit and dizzy, in fact their renal damage is serious and the creatinine is obviously increasing.


All patients with high level of creatinine should pay more attention to this condition and take positive treatment timely. In addition, the treatment should repair the damaged kidney effectively, so long as the damaged kidney is well repaired, the renal filtration function will recover and the high level of creatinine will disappear automatically.

What Are the Indications of Dialysis?

Nowadays, dialysis is extended into multiply kinds of blood purification such as hemodialysis, peritoneal dialysis, Hemofiltration, plasma exchange, etc. The indications of dialysis has been extended from Renal Failure to various kinds of serious complications by clearing away internal toxin. Besides, the indications of dialysis also includes the conditions of rescuing all kinds of poisoning patients, clearing away internal excess blood lipid. In a word, the indication of dialysis includes all the conditions of clearing away poisoning substances in serum no matter endogenous or exogenous substances. Then, what are the indications of dialysis?

The indications of dialysis are as follows:

1. the conditions of Chronic Renal Failure or Acute Renal Failure such as urea nitrogen,creatinine, hyperkalemia, acidosis, excess water, CHF(congestive heart-failure)

2. water intoxication caused by invalid Diuretics

3. Serious acidosis which can not be well controlled by medicine

4. Serious hyponatremia

5. Poisoning caused by some medicine or poison

6. Masses of ascites caused by Cirrhosis or Nephrotic Syndrome, etc, without infection of ascites

7. Acute stage of SLE

8. hepatic encephalopathy


Dialysis can help patients to eliminate internal toxin and relieve the condition of poisoning. The indications of dialysis are various, but the characteristic of dialysis is the same by clearing away internal toxin. Although dialysis can effectively relieving the poisoning condition, a long term of dialysis will bring about multiply complications, which endangers patients' lives. That is the reason why dialysis patients seek way to get rid of dialysis.

What Is the Relationship between Hypertension and Kidney Disease?

Many Kidney Disease patients suffer Hypertension(high blood pressure) and some patients with Hypertension(high blood pressure) may develop kidney disease. What is the relationship between Hypertension(high blood pressure) and Kidney disease?

Kidney disease patients often suffer Hypertension(high blood pressure). That is because the damaged renal parenchyma can active the secretion of renin, which increases the active of Angiotensin I (AGTI) causing vasoconstriction of arteriole all over the body. As a result, it leads to Hypertension. Moreover, renin and AGTI both can promote the secretion of aldosterone, leading the retention of excess water and sodium. As a result, it further increases blood volume and aggravates the condition of Hypertension(high blood pressure).

Long term of Hypertension(high blood pressure) can further damage to kidney by leading to the condition of arteriolonephrosclerosis. Besides, Hypertension can also cause the condition of ischemia and anoxia, which also injures kidney and other organs.


So patients with Hypertension(high blood pressure) should well control their blood pressure to prevent from Hypertensive Nephropathy. Kidney disease patients should take positive treatment to well control their condition, so long as their injured kidney is well repaired, Hypertension(high blood pressure) will be effectively under controlled.

The Symptoms of Chronic Nephritis in the Early Stage

The common symptoms of Chronic Nephritis are: fatigue, tired, backpain, swelling in eyelid or legs. Normally, If patients are not suffering Uremia, they will not present hydrothorax and ascites. Patients will not pay more attention to fatigue, only through the physical examination reports, the kidney disease can be diagnosed out. The symptoms of Chronic Nephritis in the early stage are diversified, some symptoms are obvious, and some are concealed.

The first symptoms of Chronic Nephritis: Hematuria

There are two kinds of hematuria: gross hematuria and microscopic hematuria. Gross hematuria means the hematuria can be seen by our gross eyes, the color of urine like washing meat, some children will present blood clot. Microscopic hematuria only can be seen by microscope, the red blood in the high power field can be found more than 1. Hematuria is the common symptoms of Chronic Children Nephritis. There are many reasons for hematuria, parents should take children go to the hospital when they found this symptom.

The second symptoms of Chronic Nephritis: Foam in urine

More foam in urine, especially little foam in the urine. That means there are proteins in the children urine. If parents don’t have certain medical knowledge, they often neglect this hint. The easiest way is do the urine test for figuring out whether it is proteinuria or not.

The Third symptoms of Chronic Nephritis:

The main reason why patients present swelling in eyelid: the kidney function of discharging and regulating water has damaged, more and more water and sodium accumulated in the human body, especially in the slack tissues like eyelid. Normally, patients have more swelling in the eyelid when they wake up in the morning, after doing some sports, this symptom disappear naturally.


Normally, we suggest patients do these checks, like urine test, blood test, renal function test etc.

How to Treat Polycystic Kidney Disease(PKD) by Micro-Chinese Medicine Osmotherapy

Polycystic Kidney Disease(PKD) is caused by the phenotype transformation of Renal Tubular Epithelial Cell (RTEC). After the pathlogical change, RTEC acts as cyst wall cell and has the function of secreting sac liquid. As there is no normal pathway to discharge the sac liquid, it accumulates in cyst gradually and the cyst grows bigger. As a result, the growing cyst has a higher intracapsular pressure, pressing its surrounding renal tissues. If this condition is not corrected timely, it will cause the condition of ischemia and anoxia, causing damage to renal intrinsic cell or even leading to Renal Failure. How can Micro-Chinese Medicine Osmotherapy treat Polycystic Kidney Disease(PKD)?

Micro-Chinese Medicine Osmotherapy treat Polycystic Kidney Disease(PKD) by inhibiting the secretion of sac liquid and promoting the reabsorption of sac liquid. Thus, it achieves the goal of shrinking cyst, inhibiting the growth of cyst. Prescriptions of Micro-Chinese Medicine Osmotherapy are super finely shattered, which makes the active ingredients more easily to permeate. With the external application of penetrant and osmosis devices, active ingredients can directly permeate into renal lesion by blood circulation. When the active ingredients enter into renal lesion, it can dilate blood vessels, promote the blood circulation on the cyst wall, enhance the permeability of renal blood vessels and reverse the condition of high intracapsular pressure. Thus the sac liquid will be reabsorbed and the cyst will shrink automatically.

Form the above information, it concludes that Micro-Chinese Medicine Osmotherapy is an external treatment without operation. After the treatment of Micro-Chinese Medicine Osmotherapy, the larger cyst will shrink and the smaller one can be inhibited effectively. Consequently, Polycystic Kidney Disease(PKD) patients can well control their condition without any operation and live a full life.

Any questions please consult our experts on line.

What Is Polycystic Kidney Diet(PKD Diet)

Proper Polycystic Kidney Diet(PKD Diet) can effectively help to slow down the development of PKD and also improve treatment effects. Then, how can PKD patients take proper diet? What Is Polycystic Kidney Diet(PKD Diet)?

Polycystic Kidney Diet(PKD Diet):One, PKD patients should take more food as follows which are beneficial to their health and the treatment effects. Those foods are as follows:

1. Fruit and vegetables which contains much vitamin

2. Fruit and vegetables which is abundant with iron

3. Food which can help to dissolve calculus

4. Food which has a function of diuretic

5. Alkaline Food which has function in assisting treatment

In addition, Polycystic Kidney Diet(PKD Diet) should avoid those foods as follows:

1. Pluck: pluck is not a proper diet for PKD patients especially animal livers. Liver is an organ for metabolizing toxin and much toxin are accumulated in it. PKD patients take this food it will aggravate burden to kidney. So PKD patients should avoid eating pluck.

2. High-protein diet: PKD patients should take low protein diet. Any high-protein diet will aggravate burden to the damaged kidney by metabolized into much of nitrogen products.

3. Wine: patients should avoid drinking wine, which can stimulate the secretion of sac liquid and promote the growth of cyst.

4. Stimulating food such as coffee, chocolate, hot pepper.

All those mentioned should be highly paid attention to. Patients should always take Polycystic Kidney Diet(PKD Diet) and take positive treatment, so long as the condition is well under controlled, PKD patients can live a full life with it.


Any more questions please read other related articles or consult our experts on line.

What is IgA Nephropathy

What is IgA Nephropathy?IgA Nephropathy is chronic glomerulus disease caused by a group of pathogenesis with the same characteristic of immunopathology. IgA Nephropathy has a great variance during its development, which starts with slight partial pathological change and represents slight membrane broadening and sectional hyperplasia among a few of glomerulus. But the pathological change of sectional hyperplasia can develop into sectional sclerosis. Some pathological change of IgA Nephropathy may be apparent together with diffusible membrane hyperplasia, occasionally with the formation of cresent. The typical characteristic of IgA Nephropathy is the deposition of IgA on mesangial area displaying immunofluorescence but rarely with the deposition of C3, IgG and IgM, which is confirmed with the deposition of electronic density substances by electron microscope.

The symptoms of IgA Nephropathy mainly display gross hematuria or microscopic hematuria, and can be accompanied with slight protein in urine, which a few patients can develop into Nephrotic Syndrome. In clinic, there are about 40 to 45 percent of patients displaying blood urine observed by naked eyes or under microscope, about 35 to 40 percent of patients can display protein in urine and blood urine under microscope, and the others display with Nephrotic Syndrome or Renal Failure. Because of the great variation of pathological types of IgA Nephropathy and glomerulus's extent of damage, patients should strictly observe the frequency of blood urine, the extent of protein in urine by naked eyes . Further more, they should also check up whether they have Hypertension and the extent of damage of renal function. Once there any abnormality is found out, patients should take the corresponding treatment.

The reasons for diagnosis of IgA Nephropathy are as follows .
One, one of the reason is the presence of protein urine with no symptoms and blood urine observed by naked eyes or under microscope after the infection of the upper respiratory tract.

Two, blood urine of glomerulus (charactered with abnormal red blood cell), protein urine with macro, moderate and mixed protein in urine, and IgA in blood increasing can be used to diagnose IgA Nephropathy.

Three, immunofluorescence mainly with granular IgA can be found in the area of glomerulus membrane by renal biopsy and immune pathologic examination.

Four, other reasons for diagnosis of IgA Nephropathy except for the reasons such as acute glomerulus nephritis by external streptococcus infection, non-IgA membrane proliferative nephritis, TBMN, LN, anaphylatic purpura nephritis and renal damage caused by cirrhosis or ALD, etc.


At present, latest research has discovered that IgA Nephropathy is closely related with the damage to renal inherent cell. So for the treatment of IgA Nephropathy, it should pay more attention to repairing and reverting the function of renal inherent cell.