2015年11月17日星期二

The Symptoms of Renal Hypertension

Hypertension can be divided into primary hypertension and secondary hypertension, which includes renal hypertension. Renal hypertension is not only a sign that the kidney’s conditions are worsening, and it would aggravate kidney conditions.
Renal hypertension can bring about many symptoms, which are listed as follows.

1. headache

The headache happens in the afterbrain in most cases, which is often accompanied with nausea and vomit.

2.vertigo

Vertigo tends to happen to females, which usually happens when they squat.

3. tinnitus

The tinnitus happens in both ears and persists for a long time.

4. palpitation

Hypertension could cause myocardial hypertrophy, cardiomegaly, MI(myocardial infarction) and cardiac insufficiency, all of which would cause palpitation.

5.insomnia

Patients with renal hypertension tend to have difficulty falling sleep, wake early, have nightmare, and are easy to wake.

6. numbness in limbs

Numbness in finger, toe or skin is very common and their fingers are not flexible.

7.unexplained tumble

As a result of hardening of cerebral blood vessels, triggering ischemia in the brain and malfunction of motor nerve, patients can present ataxia and disequilibrium.

8. epistaxis

According to medical observations, patients with hypertension tend to have repeated epistaxis.


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How Do You Get Lupus Nephritis

Lupus Nephritis is a serious complication of systemic lupus erythematosus (SLE). Many patients with Lupus Nephritis may complain that they do not have a family history of kidney disease and they are as strong as a bull in daily life, but why they get Lupus Nephritis?

Autoimmune deficiency plays a major role in the pathogenesis of Lupus Nephritis. When the external antigens like colds, infections and so on invade into body, they will activate the antibodies to fight against the antigens. However, as the autoimmunity has deficiency, the antibodies will impair the healthy tissues in body like form immune complex, activate complement, depositing in glomerular basement membrane. Alternatively, autoantibodies may bind to antigens already located in the glomerular basement membrane forming immune complexes in situ. Then the immune complexes promote an inflammatory response by activating complement and attracting inflammatory cells thus leading to inflammation of glomeruli. As a result, a large amount of protein will leak into urine leading to proteinuria, edema, and hypertension and so on.

The conventional therapies for Lupus Nephritis mainly include hypertension medicines, hormones and so on. After a period of treatment, most of the patients can get a marked improvement. However, even mild infections can trigger the disease again. That is because the medicines and hormone can only treat the symptoms of Lupus Nephritis, but can not treat the causes.


As autoimmunity deficiency plays the main role in causing Lupus Nephritis, the patients need to improve their autoimmunity and restrain the abnormal immune reaction. Moreover, the immune complexes are the harmful substances leading to inflammatory response to glomeruli. Therefore, the patients should choose therapies that can clear away the immune complexes out of body and then repair the impaired glomerular basement membrane. In this way, the patients will be able to improve their renal function enormously. What's worse, once the autoimmunity improves, it will decrease the relapsing of Lupus Nephritis. If you want to get more information about the prevention, diet of Lupus Nephritis and other aspects, you can consult our experts on line or email to kidney-treatment@hotmail.com.

Daily Care for Patients with Lupus Nephritis

Lupus Nephritis is a kidney disorder caused by systemic lupus erythematosus. As the disease is very likely to relapse, the daily care is very important for the patients with Lupus Nephritis.

1. Prevent infections: The patients with Lupus Nephritis often use steroids, immunosuppressive agents and other hormones to restrain the abnormal immune reactions. However, those medicines also can impair the healthy immunity thus causing immunity to decline. As a result, the external virus, bacteria is very early to invade into body thus leading to infections. We all know that even if a mild infection may trigger Lupus Nephritis again. Therefore, the patients with Lupus Nephritis should keep healthy daily care to prevent infections as possible as they can.

2. Take proper exercise: Proper exercise can improve blood circulation and strengthen heart and liver functions as well as keep the tenacity of bones and muscles. However, as the patients with Lupus Nephritis usually have arthritis, they should take proper exercise like jogging, bicycling and avoid excessive exercise.

3. Avoid sunshine: The patients with Lupus Nephritis are sensitive to sunshine. If they are exposed to sunlight, it can aggravate their disease. Therefore, the patients with Lupus Nephritis should avoid sunshine as possible as they can.

4. Keep a healthy diet: A healthy diet plays an important role in slowing down Lupus Nephritis progression. Generally speaking, the patients should keep a low protein and salt diet. However, as the disease conditions vary with different patients, the patients should make their personalized diet based on their lab results under their doctors' guidance.

5. Keep a good mood: Lupus Nephritis is a chronic disease. Many patients still do not have any improvement after frequent treatments. Therefore, many patients will lose the confidence in the treatment of the disease. This can discount the treatment effect and aggravate the disease. So the patients themselves should keep optimistic about their disease and other family members should pay more care to them. If so, they will be able to get a better therapeutic effect.


The above article has introduced the daily care for the patients with Lupus Nephritis. If you want to know more information like the treatment of Lupus Nephritis and other aspects, you can email to kidney-treatment@hotmail.com.

2015年11月16日星期一

How Do You Get Acute Uric Acid Nephropathy

Acute Uric Acid Nephropathy refers to kidney function decreases rapidly caused by high levels of uric acid in the urine. How do you get Acute Uric Acid Nephropathy and how to prevent it? This article will give you a clear response.

It is very common among the patients with myeloproliferative disorders and malignant tumor, especially after chemotherapy. Acute Uric Nephropathy is caused by renal tubular obstruction by urate and uric acid crystal. Under the influence of chemotherapeutic agents or radiation therapy, a lot of nucleotides are dissolved and cell lysis occurs. As a result, the uric acid level rises in a short time and may exceed 1000 umol/l. When the high uric acid level exceeds the clearance ability of kidneys, the uric acid crystals will deposit in collecting duct, pelvis and even ureter.

The crystal deposition causes increased tubular pressure, increased intrarenal pressure and extrinsic compression of the small diameter renal venous network. As a result, the resistance in renal vessels increases and the renal blood flow decreases. The increased tubular pressure and declined renal blood flow cause a decline in glomerular filtration and lead to oligoanuric Acute Renal Failure.

In order to avoid Acute Uric Acid Nephropathy, the patients with leukemia, lymphoma, multiple myeloma and other malignant tumor should take allopurinol before undergoing chemotherapy. In chemotherapy, they should keep enough water intakes and guarantee their urine output volume reaches 2000~3000 ml per day. Moreover, they should alkalify urine. If necessary, they should take some diuretic to increase the urine output.


Moreover, in some cases, acute gout also can lead to Acute Uric Acid Nephropathy. If you have a prehistory of acute gout and have abnormal symptoms like decreased urine output, you should go to relative exam to find if you have renal injury.

Side Effects of Hormone Therapy in Lupus Nephritis Treatment for Children

Lupus Nephritis is one of serious complications of lupus. More than 60% of children with lupus will develop Lupus Nephritis. If untreated, the disease will develop into Chronic Renal Failure. Therefore, once your child is diagnosed with Lupus Nephritis, an appropriate medical intervention is very necessary for preventing the disease progression. However, the conventional hormone therapy brings so many side effects to the children with Lupus Nephritis.

In most cases, the hormone therapy for the children with Lupus Nephritis is generally comprised of corticosteroids to control the inflammation of kidneys and immunosuppressive agents to reduce immune system activity. Although these hormones have obvious effects in eliminating symptoms of Lupus Nephritis, it can result in significant side effects on children.

Generally, steroids are given in high dosage until Lupus Nephritis improves. As a result, long-term and high dosage of steroids usage will lead to aggravation of high blood pressure, infections, Diabetes, nerve system, body weight again, delayed height growth. Theses complications can restrict the healthy growth of the children with Lupus Nephritis.

Moreover, the side effects of immunosuppressive agents in children should also be considered by parents. Long term use of immunosuppressive agents can increase the risk of infections. Especially, cyclophosphamide can lead to hair loss, cancer development, infertility and so on.

Therefore, before taking hormone therapy, the parents should think twice about so many side effects of hormone on their children. In order to avoid the side effects and prevent the progression of Lupus Nephritis thus promoting healthy development for the children, here Chinese herbal medicine is recommended to the children with Lupus Nephritis.

Chinese herbal medicine is a treasure in Chinese medical history with thousands years of history. At present, it has been approved by more and more foreigners. Based on the types and severity of kidney disease, the prescription is also different.

Chinese herbal medicine is mainly comprised of herbs from the nature so they do not have any side effects on the children with Lupus Nephritis.


If you are worrying about your children' Lupus Nephritis and looking forward a better therapy, please consult us on line or email to kidney-treatment@hotmail.com.

Why Do Patients on Dialysis Have Headache

Headache is a common complication of dialysis and its incidence is about 5%. The main causes of headache for the patients on dialysis are as follows:

1. Balance disturbance syndrome

Balance disturbance syndrome affects about 3~20 of the total population on dialysis and mainly occurs among the patients who start dialysis for a short time. Proper management of dialysis is the key to declining balance disturbance syndrome. The doctors should increase the sodium concentration in the dialysis fluid or add mannitol into the dialysis fluid in order to avoid balance disturbance syndrome.

2. High blood pressure

High blood pressure also can lead to headache. If the patients keep nifedipine or captopril, it will be effective to moderate high blood pressure. If their high blood pressure is out of control, they should stop dialysis at once. Once they stop dialysis, their blood pressure will recover normal, their headache will also disappear.

3. Cerebral hemorrhage

As the patients on dialysis are usually accompanied by high blood pressure and cerebral arteriosclerosis, the incidence of cerebral hemorrhage also rise accordingly. Excessive use of anticoagulant or mild trauma may cause cerebral hemorrhage. For the patients with Polycystic Kidney Disease, rupturing of cerebral aneurysm may also lead to cerebrovascular accident leading to headache. Moreover, subdural hematomas and cerebral embolism also can result in headache.

4. Other causes

In dialysis, if hemolysis occurs or the patients can not tolerate acetate and so on, they also may have headache.


Therefore, once the patients on dialysis have headache, they should reflect to their doctors at once. The doctors should find out the specific cause of headache and receive relative measures to decline the damage greatly.

2015年11月14日星期六

Is there a Better Treatment for End Stage Renal Failure than Kidney Transplant

Kidney Transplant is the main replacement treatment for the patients with End Stage Renal Failure in the conventional treatment. However, with the development of regenerative medicines, Immunotherapy becomes a better choice for the patients with End Stage Renal Failure.

No matter what the primary diseases of End Stage Renal Failure are, the root cause of renal failure is the renal functional cells fibrosis due to insufficient supplement of oxgen and blood to kidneys. Clinically, many diseases can disturb the normal oxgen supplement to kidneys. For example, in Polycystic Kidney Disease, the enlarged cysts will oppress the surrounding nephrons, Diabetes high blood glucose injury the systemic capillaries including renal capillaries and so on. Once the kidneys can not get sufficient blood supplement, the fibrosis process is initiated.

Therefore, the key in the treatment of End Stage Renal Failure is to improve blood circulation and increase the renal blood flow. On this point, Chinese medicines play an irreplaceable role.

Chinese medicines can dilate blood vessels, degrade extracellular matrix and shrink the cysts and so on. As a result, the initiating factors of renal ischemia and anoxia are blocked. Moreover, once the blood circulation improves, the renal function will be able to stop further damage. Meanwhile, Chinese medicines can supply some micronutrients for repairing the damaged renal functional cells.
However, if the cells are totally necrotic, Chinese medicines are no use for this part of cells.

If so, Immunotherapy is recommended. The patients should make use of the regeneration function of Immunotherapy to improve the renal function. Immunotherapys are the most original cells with multi-potential and multi-directional differentiation ability. After cultivated in right condition, they will be able to differentiate into new renal functional cells to replace the necrotic cells to function. Moreover, Immunotherapy can release many micronutrients that can promote the self-repairing of the damaged cells. As a result, the overall renal function will improve greatly.

The combined application of Chinese medicines and Immunotherapy brings new hope to the patients with End Stage Renal Failure and has been approved by more and more patients at home and abroad.


If you are a patient with End Stage Renal Failure and want to get more personalized guidance, please email to kidney-treatment@hotmail.com.

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